Advances in esophageal microbiota and esophageal related diseases
10.3760/cma.j.issn.0253-3766.2019.08.001
- VernacularTitle: 食管微生物与食管相关疾病研究进展
- Author:
Anqi LIU
1
;
Wen CHEN
Author Information
1. Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
- Publication Type:Review
- Keywords:
Esophagus;
Microbiota;
Flora;
Sampling method
- From:
Chinese Journal of Oncology
2019;41(8):561-564
- CountryChina
- Language:Chinese
-
Abstract:
Esophagus, as the pipe connecting oral cavity and stomach, has unique anatomical structure and physiological functions. The related diseases including esophageal cancer and precancerous lesions are the ones of major public health problems in China. The pathogenesis of esophageal diseases is still not clear. The exploration of correlation between the changes of esophageal microbiota and esophageal diseases becomes a new breakthrough in the study of etiology. Previous studies have found enrichment of gram-positive bacteria in the normal esophagus, while a decrease in diversity of bacteria and a dominant gram-negative anaerobe in diseased esophagus. Although much progress has been made in the study of esophageal microbiota, the standard method of how to accurately and noninvasively collect esophageal microbiota is still lack, which is an important part of the esophageal microbial research.
