Etiologic and epidemiologic features of acute respiratory infections in adults from Shanghai, during 2015-2017
10.3760/cma.j.issn.0254-6450.2019.08.007
- VernacularTitle: 上海市2015－2017年成年人急性呼吸道感染病例的流行病学和病原学特征分析
- Author:
Dechuan KONG
1
;
Huanyu WU
1
;
Yaxu ZHENG
1
;
Hao PAN
1
;
Chenyan JIANG
1
;
Xi ZHANG
1
;
Jian CHEN
1
;
Fan WU
1
,
2
Author Information
1. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
2. Shanghai Institutes of Preventive Medicine, Shanghai 200336, China
- Publication Type:Journal Article
- Keywords:
Acute respiratory infections;
Pathogen;
Influenza;
Epidemiological characteristics
- From:
Chinese Journal of Epidemiology
2019;40(8):904-910
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the etiologic and epidemiological characteristics of adult acute respiratory infections in Shanghai during 2015-2017.
Methods:Data was collected from outpatients with acute respiratory infections who visited the Fever Clinics in three hospitals of different levels in three administrative regions of Shanghai, from 2015 to 2017. Basic information and nasopharyngeal swabs were collected from cases in line with the inclusion criteria. Multiplex RT-PCR and bacterial cultures were performed to detect the respiratory pathogens.
Results:A total of 806 individuals were enrolled from 2015 to 2017. Respiratory pathogens were identified in 73.45% (592/806) of the cases, with the virus detection rate as 66.75% (538/806). It was found that the major respiratory pathogens for virus detection were influenza A in 326 (40.45%), influenza B in 116 (14.39%), rhinovirus/enterovirus in 39 (4.84%) of the cases. The overall detection rate of bacteria was 16.13% (130/806), including Klebsiella pneumoniae in 90 (11.17%) cases, Staphylococcus Aureus in 46 (5.71%) cases. Other kind of bacteria were not detected in our study. The detection rates on Mycoplasma pneumoniae was 5.33% (43/806) and on Chlamydia pneumonia was 0.37% (3/806). Co-infection with multiple pathogens was detected in 18.61% (150/806) of the cases, including 135 with double infection (accounting for 90.00%), 14 with triple infection and 1 with quadruple infection (accounted for 9.33% and 0.67%, respectively). Among the 150 cases with co-infections, the main identified pathogens were influenza A, Klebsiella pneumoniae, Staphylococcus aureus, and Mycoplasma pneumoniae. Pathogens of acute respiratory infections that identified among the outpatients from the Fever Clinics at different time, region or population, the characteristics were different (P<0.001).
Conclusions:In 2015-2017, outpatients with acute respiratory infections in Shanghai were mainly caused by influenza virus or other viruses, however dynamically with its composition, time, region and characteristics of the population. It is necessary to strengthen and combine related medical and preventive services and to develop the appropriate strategies regarding clinical diagnosis and treatment.
