Seasonality and etiological characteristics of infectious diarrhea in outpatients of 18 or above-year-old in Shanghai, 2014-2017
10.3760/cma.j.issn.0254-6450.2019.08.004
- VernacularTitle: 上海市2014－2017年成年人感染性腹泻门诊病例的季节分布及病原学特征分析
- Author:
Xiaohuan GONG
1
;
Hongyou CHEN
1
;
Wenjia XIAO
1
;
Sheng LIN
1
;
Yuan ZHUANG
1
;
Xiaozhou KUANG
1
;
Zheng’an YUAN
1
;
Fan WU
1
,
2
;
Hao PAN
1
;
Huanyu WU
1
Author Information
1. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
2. Shanghai Institutes of Preventive Medicine, Shanghai 200336, China
- Publication Type:Journal Article
- Keywords:
Diarrhea;
Comprehensive surveillance;
Seasonality;
Etiology;
Circular distribution;
Concentration ratio
- From:
Chinese Journal of Epidemiology
2019;40(8):889-894
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the seasonality and etiological characteristics of infectious diarrhea in adults from Shanghai.
Methods:Adult patients with diarrhea who had visited the enteric disease clinics in 22 hospitals that carrying on the Diarrhea Comprehensive Surveillance sentinel programs in Shanghai during 2014-2017, were surveyed. Stool specimens were collected according to the different intervals of sampling and detected for 12 bacteria and 5 viruses. Concentration ratio and circular distribution method were used for data analysis.
Results:From 2014 to 2017, a total of 9 573 stool specimens were collected from the targeted diarrhea patients ≥18 years old (n=96 067), through the Shanghai Diarrhea Comprehensive Surveillance program. The positive rate of detection was 46.44%. Seasonal peaks of infectious diarrhea were both seen in summer (bacteria peak, diarrheagenic Escherichia coli and Vibrio parahaemolyticus, etc.) and in winter (virus peak, Norovirus, etc.). Both bacterial and viral infections presented seasonal concentration (Raleigh’s test P<0.001) but more obvious with bacterial infection. Viral infection accounted for 60.19% of the cause of infectious diarrhea. The top five predominant pathogens appeared as Norovirus, Rotavirus, diarrheagenic Escherichia coli, Vibrio parahaemolyticus, and Salmonella spp..
Conclusions:Among the adult outpatients with infectious diarrhea in Shanghai, obvious seasonality was seen, with peaks in both summer and winter. Viral infection with Norovirus in particular, appeared as the predominant source of infection. Active, continuous and comprehensive diarrhea-related surveillance programs would be able to monitor the changing dynamic of pathogen spectrum, and lead to the adoption of targeted preventive measures.
