Development and validation of a simplified height-specific blood pressure cutoffs table for screening hypertension in Chinese children and adolescents
10.3760/cma.j.issn.0253-9624.2019.07.009
- VernacularTitle: 儿童青少年身高别高血压筛查界值简化表的制定与验证
- Author:
Yaping HOU
1
;
Qin LIU
2
;
Liu YANG
1
;
Min ZHAO
3
;
Xinnan ZONG
4
;
Bo XI
1
Author Information
1. Department of Epidemiology, School of Public Health, Shandong University/Children Cardiovascular Research Center of Shandong University, Ji′nan 250012, China
2. Department of Ultrasound, Capital Institute of Pediatrics, Beijing 100020, China
3. Department of Nutrition and Food Hygiene, School of Public Health, Shandong University, Ji′nan 250012, China
4. Department of Child Growth and Development, Capital Institute of Pediatrics, Beijing 100020, China
- Publication Type:Journal Article
- Keywords:
Hypertension;
Child;
Adolescent;
Cross-sectional studies;
Cut-offs
- From:
Chinese Journal of Preventive Medicine
2019;53(7):701-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop and validate a simplified height-specific blood pressure cutoffs table for screening hypertension in Chinese children and adolescents.
Methods:We developed a simplified height-specific blood pressure cut offs table according to Chinese Blood Pressure Reference for Children and Adolescents aged 7-18 years (WS/T 610-2018) (hereafter referred to as "complex definition"). Populations from Early Warning, Diagnosis and Treatment of Children Cardiovascular Disease Project ("Ji′nan sample") and Shandong Children Cardiovascular Cohort Study Project ("Zibo sample") were used as validation populations for evaluating the screening effect of the simplified table for elevated blood pressure and hypertension in children and adolescents.
Results:We developed simplified height-specific blood pressure cutoffs table including 7 height groups and 28 cutoffs. Both Ji′nan and Zibo samples were selected by convenient sampling method, and the former included 7 233 participants aged 7 to 17 years, among whom 3 790 (52.4%) were boys. Latter population included 1 277 participants aged 7 to 11 years, among whom 681 (53.3%) were boys. The simplified table performed well for identifying elevated blood pressure in Ji′nan sample, with values of area under the receiver operating curve (AUC) (95%CI), sensitivity, specificity, and Kappa statistic as 0.96 (0.95-0.97), 93.0%, 98.5% and 0.91, respectively, which were similar with results in Zibo sample [the values were 0.92 (0.90-0.95), 87.0%, 98.0% and 0.85, respectively]. The simplified table also performed well for identifying hypertension in Ji′nan sample with values of AUC (95%CI), sensitivity, specificity, and Kappa statistic as 0.92 (0.91-0.94), 86.9%, 98.1% and 0.85, respectively, which were similar with results in Zibo sample [the values were 0.94 (0.91-0.96), 88.2%, 98.9% and 0.88, respectively].
Conclusion:Screening for elevated and high blood pressure based on simplified height-specific blood pressure cutoffs table is easy to use and it shows satisfying effect.
