Expert consensus on rabies exposure prophylaxis
10.3760/cma.j.issn.0253-9624.2019.07.004
- VernacularTitle: 狂犬病暴露预防处置专家共识
- Author:
Wenwu YIN
1
;
Chuanlin WANG
2
;
Qiulan CHEN
1
;
Guanmu DONG
3
;
Yuhua LI
3
;
Wuyang ZHU
4
;
Si LIU
5
;
Qingjun CHEN
6
;
Xinjun LYU
4
;
Zhenggang ZHU
7
;
Xiaoyan TAO
4
;
Yu LI
1
;
Di MOU
1
;
Xianjun WANG
8
Author Information
1. Infectious Disease Management Department, Chinese Center for Disease Control and Prevention, Beijing 102206, China
2. Emergency Department/Trauma Center, Peking University People′s Hospital, Beijing 100044, China
3. Department of Arboviruses and Rabies, National Institute for Food and Drug Control, Beijing 102629, China
4. Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
5. Emergency Department, First Hospital of Peking University, Beijing 100034, China
6. Emergency Department, Beijing Hepingli Hospital, Beijing 100013, China
7. Rabies Clinic, Wuhan Center for Disease Control and Prevention, Wuhan 430015, China
8. Institute for Viral Disease Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan 250014, China
- Publication Type:Guideline
- Keywords:
Rabies;
Lyssavirus;
Post-exposure prophylaxis;
Vaccine;
Immunoglobulin
- From:
Chinese Journal of Preventive Medicine
2019;53(7):668-679
- CountryChina
- Language:Chinese
-
Abstract:
Rabies is a zoonotic infectious disease caused by lyssavirus and characterized by central nervous system symptoms. The fatality rate of rabies is almost 100%. About 59 000 cases die of rabies worldwide every year, mainly in Asia and Africa. China is an epidemic country of rabies. Grade II and III exposures are the main types of rabies exposures in China. Standardized post-exposure prophylaxis (PEP) can prevent rabies almost 100%. Human Rabies Vaccine Technical Working Group, National Immunization Advisory Committee and invited experts reached an expert consensus on PEP by referring to the World Health Organization′s position paper on rabies vaccine in 2018 and related research progress in recent.