Research progress in environmental factors of nonsyndromic orofacial clefts
10.3760/cma.j.issn.1009-4598.2019.07.017
- VernacularTitle: 非综合征性唇腭裂环境因素的研究进展
- Author:
Yanru HAO
1
;
Yan WANG
;
Xiaomei SUN
Author Information
1. Department of Stomatology, Plastic Surgery Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100144, China
- Publication Type:Review
- Keywords:
Nonsyndromic orofacial clefts;
Drug;
Supplementation intake;
Negative life events;
Social support;
Environmental pollution;
Occupational exposure
- From:
Chinese Journal of Plastic Surgery
2019;35(7):702-705
- CountryChina
- Language:Chinese
-
Abstract:
Nonsyndromic orofacial clefts (NSOC) is a common but complicated congenital malformation, resulted from complex interplay of genetic and environmental factors. In this study, certain environmental factors was demonstrated, including drug, supplementation intake, occupational exposure, environmental pollution and psychosocial factor, to be associated with increasing risk of NSOC.