Application of acute gastrointestinal injury grading system in assessing the severity of acute pancreatitis
10.3760/cma.j.issn.1674-1935.2019.06.005
- VernacularTitle: 急性胃肠损伤分级在急性胰腺炎患者严重程度评估中的应用
- Author:
Yanbo ZENG
1
;
Dongjie FAN
2
;
Yiqi DU
1
Author Information
1. Department of Gastroenterology, Changhai Hospital, Navy Medical University, Shanghai 200433, China
2. Department of Gastroenterology, Shanghai First People′s Hospital Baoshan Branch, Shanghai 200940, China
- Publication Type:Journal Article
- Keywords:
Pancreatitis, acute necrotizing;
Acute gastrointestinal injury;
Forecasting
- From:
Chinese Journal of Pancreatology
2019;19(6):416-419
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of acute gastrointestinal injury(AGI) grading system in assessing the severity, infectious pancreatic necrosis and death of patients with moderate severe acute pancreatitis (MSAP) and severe acute pancreatitis (SAP).
Methods:The clinical data of 344 patients with MSAP or SAP admitted in Changhai Hospital Affiliated to Navy Medical University from June 2011 to June 2015 were collected. ROC curve was used and the area under ROC curve (AUC) was calculated. The predictive value of AGI grade for the severity, infectous pancreatic necrosis and death was compared with those of different clinical scores(APACHEⅡ score, MCTSI and Marshal score).
Results:Of 344 patients, 81 patients were classified into high AGI grade group (Grade Ⅲ, Ⅳ), while 263 patients were in low AGI grade group(Grade Ⅰ, Ⅱ). The mortality and the number of patients with organ failure were obviously higher in high AGI grade group than those in low AGI grade group (25/81 vs 0/263, 36/45 vs 32/231), and the difference was statistically significant (all PCI 0.916-0.972) and0.779(95% CI 0.723-0.836), respectively, which was higher than those of APACHEⅡ and Marshall score.
Conclusions:AGI grading system can be applied to better assess the severity of acute pancreatitis, and its predictive value for death and infectious pancreatic necrosis was higher than that of APACHEⅡ, MCTSI and Marshall score.
