Stent assisted percutaneous endoscopic necrosectomy for treating infected pancreatic necrosis
10.3760/cma.j.issn.1674-1935.2019.06.004
- VernacularTitle: 经皮支架辅助内镜下坏死组织清除术治疗胰腺坏死组织感染
- Author:
Peng WANG
1
;
Gang LI
2
;
Lu KE
2
;
Bo YE
2
;
Jing ZHOU
2
;
Zhihui TONG
2
;
Weiqin LI
1
,
3
Author Information
1. Department of General Surgery, Jinling Hospital, First School of Clinical Medicine, Southern Medical University (General Hospital of Esatern Theater Command), Nanjing 210002, China
2. Department of General Surgery, Affiliated Jinling Hospital, Medical School of Nanjing University(General Hospital of Esatern Theater Command), Nanjing 210002, China
3. Department of General Surgery, Affiliated Jinling Hospital, Medical School of Nanjing University(General Hospital of Esatern Theater Command), Nanjing 210002, China
- Publication Type:Journal Article
- Keywords:
Pancreatitis, acute necrotizing;
Infected pancreatic necrosis;
Drainage;
Percutaneous endoscopic necrosectomy;
Stents
- From:
Chinese Journal of Pancreatology
2019;19(6):411-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feasibility and safety of stent-assisted percutaneous endoscopic necrosectomy (SAPEN) in the treatment of infected pancreatic necrosis (IPN).
Methods:The patients with severe acute pancreatitis (SAP) who received the treatment of SAPEN for IPN were sequentially included from January 2018 to September 2018 in the Eastern Theater General Hospital of People′s Liberation Army. The demographic and clinical data were analyzed. The mortality and incidence of major organ dysfunctions were used as the primary observation endpoints.
Results:A total of 40 IPN patients were enrolled including 27 men and 13 women. The percutaneous covered stent placement procedures were successful in all cases; the median number of SAPEN operations was 1 (range 1-3), and no operation-related complications occurred. 32 patients were successfully cured by SAPEN, and the treatment effective rate was 80.0%. 5 patients (12.5%) required further open surgery after SAPEN. 12 patients developed new important organ dysfunction and 6 patients eventually died.
Conclusions:SAPEN was an effective and feasible minimally invasive method for the treatment of IPN, but its technical advantages still need to be further validated in large scale studies.
