Advances in new type of biomolecular markers for liver fibrosis
10.3760/cma.j.issn.1007-3418.2019.06.004
- VernacularTitle: 肝纤维化新型分子标志物的研究进展
- Author:
Wei HONG
1
;
Tao HAN
2
;
Zhemin SHI
1
;
Kun ZHANG
1
Author Information
1. School of Basic Sciences, Tianjin Medical University, Tianjin 300070, China
2. Tianjin Third Central Hospital, Tianjin Key Laboratory of Artificial Cells, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin 300170, China
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Exosomes;
Non-coding RNA;
Biomarkers
- From:
Chinese Journal of Hepatology
2019;27(6):411-414
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrosis is a common pathological process of chronic liver disease, and the number of deaths from liver cirrhosis, liver failure and liver cancer is increasing year-by-year worldwide. Presently, the detection methods to evaluate hepatic fibrosis mainly include hepatic histological examination, imaging and serum markers, but all these have many limitations in clinical aspects. Recently, there have been more and more studies related to the development of non-coding RNA, exosomes and liver fibrosis that are considered as a new type of biomolecular markers with potential clinical application. Herein, we did a preliminary assessment in conjunction with relevant advances to provide a reference for the early diagnosis and treatment of liver fibrosis.
