Characteristics of optical coherence tomography of lamellar hole-associated epiretinal proliferation
10.3760/cma.j.issn.1005-1015.2019.06.013
- VernacularTitle: 板层黄斑裂孔相关视网膜前增生膜光相干断层扫描图像特征
- Author:
Ting LUO
1
;
Yuzhong CUI
;
Xin YANG
;
Tingting HUANG
Author Information
1. Department of Ophthalmology, The Third People's Hospital of Chengdu, Chengdu 610014, China
- Publication Type:Journal Article
- Keywords:
Retinal perforations;
Tomography,optical coherence;
Epiretinal proliferation membrane
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(6):584-587
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the OCT characteristics of lamellar hole-associated epiretinal proliferation (LHEP).
Methods:A retrospective case analysis. A total of 128 patients (133 eyes) with lamellar macular hole (LMH) and 202 patients (212 eyes) with full-thickness macular hole (FTMH) diagnosed by the examinations of spectral-domain OCT (SD-OCT) in Department of Ophthalmology, The Third People's Hospital of Chengdu from January 2013 to December 2016 were included in this study. Among 133 eyes with LMH, there were 53 eyes (39.8%) with LHEP and 80 eyes (60.2%) without LHEP. Among 212 eyes with FTMH, there were 12 eyes (5.7%) with LHEP and 200 eyes (94.3%) without LHEP. The mean age of LMH with or without LHEP patients were 70.88±10.98, 64.76±13.60 years old, respectively. The difference of mean age between LMH with or without LHEP patients was statistically significant (U=1521.5, P=0.006). The inner diameter, median diameter and base thickness of the LMH, the height, base diameter and minimum diameter of FTMH were measured by SD-OCT. The traction index (THI) and the macular hole index (MHI) were calculated. An independent sample t-test or rank-sum test was used to compare the inner diameter, median diameter, and base thickness of the LMH in patients with or without LHEP, and χ2 test was used to compare the injury rate of ellipsoid zone.
Results:Of the LMH patients with or without LHEP, the inner diameter were 611.15±209.83 and 521.70±198.05 μm, the median diameter were 961.22±571.09 and 497.01±172.30 μm, the base thickness were 99.83±38.69 and 154.12±43.17 μm. The differences of the inner diameter, median diameter and the base thickness between LMH patients with or without LHEP were statistically significant (t=2.490, 5.747, -7.395; P=0.014, 0.000, 0.000). Among the 53 eyes with LHEP, There were 50 eyes (94.34%) were injured in ellipsoid zone among 53 eyes with LHEP, while 17 eyes (21.25%) were injured in ellipsoid zone among 80 eyes without LHEP. The injury rate of ellipsoid zone between LMH patients with or without LHEP was statistically significant (χ2=68.126, P=0.000). In 12 eyes of FTMH with LHEP, there were 10 eyes with THI <1.0 and MHI<0.5.
Conclusion:Compared with the LMH without LHEP, the LMH with LHEP has larger inner diameter and median diameter, thinner base and higher injury rate of ellipsoid zone.
