Vaginal tubulo-squamous polyp: a clinicopathological analysis of four cases
10.3760/cma.j.issn.0529-5807.2019.06.008
- VernacularTitle: 阴道壁管状鳞状上皮息肉四例临床病理学分析
- Author:
Feng ZHOU
1
;
Haiyan SHI
;
Yun LIANG
;
Xiaoduan CHEN
Author Information
1. Department of Pathology, Women′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China
- Publication Type:Journal Article
- Keywords:
Vaginal diseases;
Polyps;
Diagnosis, differential
- From:
Chinese Journal of Pathology
2019;48(6):462-465
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate clinicopathological characteristics of vaginal tubulo-squamous polyp (TSP).
Methods:Clinical and pathological data of 4 cases of vaginal TSP diagnosed at Women′s Hospital, School of Medicine, Zhejiang University from 2007 to 2018 were analyzed by hematoxylin-eosin and EnVision two-step immunohistochemical staining technique.
Results:The age of the 4 patients ranged from 62 to 71 years, with a mean of 66 years. Histologically, the polyps consisted of an admixture of squamous epithelium and tubules within a fibrous stroma. Immunohistochemically, the cells lining the tubules showed positive staining of prostatic acid phosphatase (PSAP) and/or prostate-specific antigen (PSA) in all 4 cases. Available follow-up in 3 patients for 4 to 6 months (mean of 5.3 months) showed no tumor recurrence.
Conclusion:TSP is an under-recognized benign vaginal polypoid disease that may develop from paraurethral Skene glands.
