Clinical effects of Dermatix Ultra silica gel and asiaticoside cream on hyperplastic scar tissue in patients after epicanthoplasty
10.3760/cma.j.issn.1671-0290.2019.06.018
- VernacularTitle: 倍舒痕硅凝胶和积雪苷霜治疗内眦赘皮矫正术后瘢痕增生的疗效
- Author:
Xia GAO
1
;
Jinde LIN
;
Lu SUN
;
Ye REN
Author Information
1. Department of Plastic and Aesthetic Surgery, Friendship Plastic Surgery Hospital, Nanjing Medical University, Nanjing 210009, China
- Publication Type:Clinical Trail
- Keywords:
Cicatrix;
Hyperplasia;
Asiaticoside;
Silica gel;
Epicanthous
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2019;25(6):508-511
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of Dermatix Ultra silica gel and asiaticoside cream for the treatment or repair of scar hyperplasia which was external used in internal corner incision of patients after the internal canthus correction operation.
Methods:A total of 90 patients were randomly chosen and divided into three groups. All patients with epicanthus were treated with the same internal canthus correction method by one doctor. There were 30 patients in each group: 30 cases in the control group were treated without any medication, and the postoperative incision healed naturally; 30 cases were treated with Dermatix Ultra silica gel; 30 cases were treated with asiaticoside cream. Patient and observer scar assessment scale (POSAS) was used as the end points to evaluate the clinical efficacy of Dermatix Ultra silica gel and asiaticoside cream 4 weeks and 12 weeks after the operation. The satisfactory degree from all the patients were collected after 6 months follow-up and we compared the scores of three groups.
Results:Compared with the control group, the POSAS scores in Dermatix Ultra silica gel group and asiaticoside cream group were low (P<0.05) at 4 weeks and 12 weeks after operation. At 4 weeks after operation, the POSAS score in Dermatix Ultra silica gel group was lower than that in the asiaticoside cream group (P<0.05). At 12 weeks after operation, there was no significant difference in POSAS score between Dermatix Ultra silica gel group and asiaticoside cream group (P>0.05). Follow-up for 6 months, the satisfaction degree of patients in Dermatix Ultra silica gel group and asiaticoside cream group was higher than in the control group (P<0.05); the satisfactory degree of patients in Dermatix Ultra silica gel group was higher than that in asiaticoside cream group (P<0.05).
Conclusions:Dermatix Ultra silica gel and asiaticoside cream have good clinical effects in repair of scar tissue after the epicanthoplasty. Dermatix Ultra silica gel is better than asiaticoside cream in scar early improvement.
