CT features of primary mediastinal neuroendocrine carcinoma
10.3760/cma.j.issn.1674-6090.2019.06.009
- VernacularTitle: 原发性纵隔神经内分泌癌CT表现特征
- Author:
Meng LI
1
;
Jie YU
2
;
Chongyong XU
3
;
Qiande QIU
2
Author Information
1. Department of Radiology, Yueqing People’s Hospital of Zhejiang, Yueqing 325600, China
2. Department of Radiology, Wenzhou People’s Hospital of Zhejiang Province, Wenzhou 325000, China
3. Department of Radiology, the Affiliated Second Hospital of Wenzhou Medical University of Zhejiang Province, Wenzhou 325000, China
- Publication Type:Journal Article
- Keywords:
Mediastinal neoplasms;
Neuroendocrine carcinoma;
Tomography;
X-ray computed
- From:
Chinese Journal of Endocrine Surgery
2019;13(6):483-487
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the CT features of primary mediastinal neuroendocrine carcinoma and improve the diagnostic accuracy.
Methods:CT findings of 12 patients with primary mediastinal neuroendocrine carcinoma diagnosed by clinic and pathology were retrospectively analyzed. The location, size, growth pattern, density, degree of enhancement, invasion of surrounding tissues and metastasis of the tumor were observed, a control analysis was performed.
Results:Among the 12 cases, 4 cases were located in the anterior superior mediastinum, 4 cases in the middle superior mediastinum and 4 cases in the middle mediastinum. There were 5 cases on the left side, 4 cases on the right side and 3 cases in the middle. The maximum diameter of the tumor ranged from 1.5 cm to 12.0 cm, with an average of (6.74±3.65) cm. The tumors were round or quasi-round in 6 cases, irregular in 6 cases, clear boundary in 9 cases and unclear in 3 cases. Uniform density was found in 6 cases. The density was heterogeneous in 6 cases, including necrosis and cystic degeneration in 4 cases, and fine-grained calcification in 1 case. The average CT value of plain scan was (38±4.8) HU. There was 1 case of perivascular growth, 2 cases of adjacent vascular compression, 3 cases of adjacent pleural invasion, and 6 cases of infiltrating the surrounding fat space. After contrast enhancement, all cases showed mild and moderate enhancement, including 4 cases with homogeneous enhancement and 8 cases with heterogeneous enhancement. After contrast enhancement, the mean CT value was (55±7.7) HU. There were 9 cases with mild enhancement and 3 cases with moderate enhancement. There were 3 cases with small linear abnormally enhanced vascular shadow in the tumor, and 4 cases with no enhancement both in the central necrosis and the cystic areas. There were 7 cases of typical carcinoid, 2 cases of atypical carcinoid, 2 cases of small cell carcinoma and 1 case of large cell neuroendocrine carcinoma.
Conclusion:Primary mediastinal neuroendocrine carcinoma is mainly located in the anterior-mediastinum. When the tumor is large, necrosis, cystic degeneration and invasive growth are easy to occur. The enhanced scan shows mild and moderate enhancement. Combined with clinical history, it can improve the accuracy of diagnosis.
