Follow-up analysis on change of serum total cholesterol concentration in rural residents in Shanxi province
10.3760/cma.j.issn.0254-6450.2019.05.010
- VernacularTitle: 山西省农村地区居民血清总胆固醇水平追踪分析
- Author:
Pengkun SONG
1
;
Jing CHEN
2
;
Xiaogang XU
3
;
Kui DONG
4
;
Yi ZHAI
5
;
Mei ZHANG
6
;
Yanfang ZHAO
6
;
Zhuoqun WANG
6
;
Shengquan MI
7
;
Jian ZHANG
1
;
Wenhua ZHAO
1
Author Information
1. National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China
2. Shanxi Provincial Center for Disease Control and Prevention, Taiyuan 030012, China
3. Wuzhai County Center for Disease Control and Prevention of Shanxi Province, Wuzhai 036200, China
4. Linyi County Center for Disease Control and Prevention of Shanxi Province, Linyi 044100, China
5. Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing 100070, China
6. National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
7. College of Health and Environment, Beijing Union University, Beijing 100023, China
- Publication Type:Journal Article
- Keywords:
Cholesterol;
Adults;
Cohort study
- From:
Chinese Journal of Epidemiology
2019;40(5):542-547
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the longitudinal change of serum total cholesterol concentration in 733 rural residents in Shanxi province.
Methods:Based on the residents of five rural areas in Shanxi province who participated in China nutrition and health survey in 2002, a follow-up survey was conducted in 2015. Fasting venous blood of the participants was collected and serum TC concentration was tested by cholesterol oxidase method.
Results:Of 733 participants, 332 were male and 401 were female. In 2002 baseline survey, the age of the participants was (42.6±9.5) years old, 76.2% of male and 83.8% of female had junior middle school education or below. Proportion of smoking were 65.7% and 1.2%, drinking were 26.8% and 4.0%, obesity were 6.3% and 12.0%, and central obesity were 27.1% and 31.9%, respectively in male and female. The follow-up age of participants in 2015 was (55.8±9.5) years old, proportion of smoking changed to 48.2% and 1.5%, drinking were 49.7% and 3.0%, obesity increased to 11.8% and 18.2% and central obesity increased to 41.6% and 53.6%, respectively in male and female. The overall serum TC level increased from (3.82±0.89) mmol/L to (4.72±0.97) mmol/L with an average increase of 27.2%, which increased from (3.84±0.94) mmol/L to (4.54±0.93) mmol/L in male with an average increase of 22.7%, and increased from (3.81±0.84) mmol/L to (4.86±0.98) mmol/L in female with an average increase of 30.9%. The serum TC levels in 18-, 30-, 40-, and 50-59 years old group increased from (3.42±0.83), (3.72±0.77), (3.90±0.83) and (4.00±1.03) mmol/L to (4.38±1.01), (4.79±0.92), (4.73±0.99) and (4.76±0.96) mmol/L, with average increase range of 31.4%, 32.1%, 25.2% and 22.6%, respectively. The mean serum TC levels between two years all had statistically significant difference among groups of gender, age, education, marital status, family history of cardiovascular disease, smoking, drinking, BMI and waist circumference after paired t-test and ANOVA analysis (P<0.01).
Conclusion:The longitudinal serum TC level of rural residents in Shanxi province increased rapidly.