The clinical application of ultra-pulsed CO2 laser skin abrasion combined with micro-skin grafting in the treatment of skin depigmentation
10.3760/cma.j.issn.1009-4598.2019.05.005
- VernacularTitle: 超脉冲二氧化碳激光皮肤剥脱结合微粒皮移植治疗皮肤色素脱失
- Author:
Shuai CHEN
1
;
Minghuo XU
1
;
Ping JIANG
2
;
Huifeng SONG
1
;
Quanwen GAO
1
;
Fang WANG
1
;
Ruijuan ZHANG
1
;
Jiajia ZENG
2
Author Information
1. Department of Burn and Plastic, Fourth Medical Center of PLA General Hospital, Beijing 100039, China
2. Department of Plastic Surgery, Nanfang Hospital, Guangzhou 510515, China
- Publication Type:Journal Article
- Keywords:
Carbon dioxide laser therapy;
Exfoliation;
Depigmentation;
Pigment cells;
Granular skin grafting
- From:
Chinese Journal of Plastic Surgery
2019;35(5):441-446
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical application of ultra-pulsed CO2 laser skin abrasion combined with micro-skin graft in the treatment of skin depigmentation.
Methods:From January 2010 to June 2014, depigmented skin specimens were used for ultra-pulsed CO2 laser skin abrasion treatment, at 0, 10, 20, 30, 40, 50, 60 mJ. HE stain was performed to observe the abrasion depth under the 100 times microscope view. The most appropriate parameter was set to completely remove the epidermis, and leave dermis undamaged. From January 2011 to December 2017, 16 patients with skin depigmentation, 12 males and 4 females, aged 12-47 years, were treated with super-pulsed carbon dioxide laser and autologous microdermis transplantation. At 1, 3, 6 and 12 months after the operation, patients′ photos were record. The color improvement was analyzed using Image-Pro Plus 6.0 software.
Results:The laser energy for complete epidermis removal is different at different sites. It is 50 mJ for back skin, 40 mJ for face and hand skin and 30 mJ for neck skin. After one year of follow-up, there was no hypertrophy scar caused by over-abrasion in all 16 patients. Combined with the micro-skingrafting, 15 patients with skin depigmentation were completely resolved, with more than 90%color improvement rate. The improvement rate was 75% in a patient with un-uniform appearance, due to part failure of micro-skin graft. The neck movement and uncertain fixation were the reasons.
Conclusions:The appropriate energy parameters can control the abrasion depth to avoid the hypertrophic scar. Combined with micro-skin graft, the depigmentation area can be improved with uniform color and reliable effect.
