Epidemiological characteristics and etiology of herpangina cases in Xi’an, 2016
10.3760/cma.j.issn.1003-9279.2019.05.007
- VernacularTitle: 2016年西安市疱疹性咽峡炎的流行特征和病原学分析
- Author:
Zerun XUE
1
;
Rui WU
1
;
Huiling DENG
2
;
Fen ZHANG
3
;
Yinjuan HUANG
1
;
Hailong CHEN
1
;
Yuewen HAN
1
;
Yujie YANG
1
;
Yangni DENG
1
;
Chaofeng MA
1
Author Information
1. Xi′an Municipal Center for Disease Control and Prevention, Xi′an 710054, China
2. 2nd Department of Infectious Diseases, Xi'an Children’s Hospital, Xi’an 710000, China
3. Maternal and Child Health Care Hospital of Huyi District, Xi′an 710300, China
- Publication Type:Journal Article
- Keywords:
Herpangina;
Epidemiological characteristics;
Enterovirus;
Etiological structure
- From:
Chinese Journal of Experimental and Clinical Virology
2019;33(5):478-481
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the epidemiological characteristics and etiologic agent of herpangina in Xi’an in 2016.
Methods:Herpangina epidemiological data and random stool samples were collected from two sentinel hospitals. The data were statistically analyzed with Excel and SPSS 18.0 and samples were detected and enteroviruses were genotyped using real-time PCR and RT-snPCR.
Results:Totally 421 cases were reported and the male-to-female ratio was 1.54∶1, age ranged from 3 month to 13 years, and 90.50% were under three years of age. Herpangina showed semiannual peaks in April to October, of which the highest was in June (23.75%, 100/421). Lab result showed that 71.05% were EV positive out of 152 samples, and further genotyping indicated 60 were non-typable, and other 48 comprised of eight serotypes of EV including EV-A71, CV-A4, CV-A5, CV-A6(6.48%), CV-A10(23.15%), CV-A12, CV-A16 and CV-B3.
Conclusions:Male children under 3 years of age were the main population and herpangina cases were most frequently reported in June in Xi’an in 2016. CV-A6 and CV-A10 were more frequently detected in the typable ones.
