Trends on the epidemics of acute meningitis and encephalitis among population under 18 years-old in Shijiazhuang city, 2007-2017
10.3760/cma.j.issn.0254-6450.2019.04.009
- VernacularTitle: 石家庄市2007－2017年18岁以下人群急性脑炎脑膜炎流行趋势
- Author:
Jianhua GUO
1
;
Jing LI
2
;
Xin ZHANG
3
Author Information
1. Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang 050011, China
2. Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang 050021, China
3. Hebei Provincial Children Hospital, Shijiazhuang 050030, China
- Publication Type:Journal Article
- Keywords:
Acute meningitis and encephalitis;
Epidemic trends
- From:
Chinese Journal of Epidemiology
2019;40(4):417-421
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the trends on the epidemics of acute meningitis and encephalitis (AME) among children under 18 years-old in Shijiazhuang city, 2007-2017.
Methods:Surveillance programs on acute meningitis and encephalitis (AMES) had been conducted in population less than 18 years-old, since 2007. Hospitals at county level or above in Shijiazhuang had been included to carry out the epidemiologic surveillance, including 6 on pathogens, regarding AMES. Qualitative description was performed to describe the epidemiologic patterns and pathogenic spectrums. Annual percent change (APC) was used to demonstrate the secular trends of AME.
Results:In 2007-2017, 11 222 locally developed AME cases that younger than 18 years-old, were reported in Shijiazhuang, with the annual average incidence rate as 108.62/100 000 (1 021/939 974) and APC as 4.81%(95%CI: 3.90%-5.93%)(t=23.01, P<0.001). Age-specific incidence appeared the highest among 4-5 years-old (242.96 cases per 100 000 children per year). Significant differences were found among children of other aged years except aged 0- years (aged 1- years t=20.21, P=0.004; aged 2- years t=19.41, P=0.006; aged 3- years t=23.50, P<0.001; aged 4- years t=31.76, P<0.001; aged 5- years t=18.53, P=0.008; aged 10-17 years t=12.82, P=0.023). The ratio of male to female was 1.46 ∶ 1 (6 652/4 570). The ratio of urban to rural cases was 0.28 ∶ 1 (2 456/8 766). A total of 57.73% (6 478/11 222) of the cases were seen between June and September. The overall positive rate of pathogens was 20.07% (658/3 123) among these patients. The top five pathogens appeared as Enterovirus (44.68%, 264/658), Cryptococcus neoformans (9.12%, 60/658), Japanese encephalitis virus (8.66%, 57/658), Streptococcus pneumoniae (6.99%, 47/658) and Varicella-zoster virus (6.69%, 44/658).
Conclusions:AME seriously harms the health of population under 18 years-old in Shijiazhuang city, with aged 3- years, aged 4- years in particular. Continued improvement on surveillance and expanded immunization are important to AME prevention and control.
