A prospective cohort study on the duration of sleep and risk of all-cause mortality among patients with type 2 diabetes

Yijia Chen; Jian SU; Yu Qin; Ying LI; Enchun Pan; Yan Gao; Ning Zhang; Jinyi Zhou; Xiaojin YU; Ming WU; Chong Shen

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A prospective cohort study on the duration of sleep and risk of all-cause mortality among patients with type 2 diabetes

VernacularTitle: 睡眠时间和2型糖尿病患者死亡风险的前瞻性队列研究
Author: Yijia CHEN ¹ ; Jian SU ² ; Yu QIN ² ; Ying LI ¹ ; Enchun PAN ³ ; Yan GAO ⁴ ; Ning ZHANG ⁵ ; Jinyi ZHOU ² ; Xiaojin YU ¹ ; Ming WU ^{1
,

6} ; Chong SHEN ⁷
Author Information

1. School of Public Health, Southeast University, Nanjing 210009, China
2. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
3. Huai’an City Center for Disease Control and Prevention of Jiangsu Province, Huai’an 223001, China
4. Suzhou City Center for Disease Control and Prevention, Suzhou 215004, China
5. Changshu City Center for Disease Control and Prevention of Jiangsu Province, Changshu 215500, China
6. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
7. School of Public Health, Nanjing Medical University, Nanjing 211166, China
Publication Type:Journal Article
Keywords: Diabetes mellitus, type 2; Sleep duration; Mortality; Prospective study
From: Chinese Journal of Epidemiology 2019;40(4):394-399
CountryChina
Language:Chinese
Abstract: Objective:To investigate the relationship between duration of sleep and all-cause mortality in patients with type 2 diabetes.
Methods:A total of 17 452 type 2 diabetic patients who were under the National Basic Public Health Service Project, in Changshu county, Qinghe district and Huai’an district in Huai’an city of Jiangsu province, were recruited as participants. Cox proportional hazards regression models were used to estimate the associations between different levels on the duration of sleep and all-cause mortality. Stratified analysis was performed according to factors as gender, age, and lifestyle.
Results:Among the 67 912 person-years of observation, from the fo1low- up program, the median time of follow-up was 4 years, with 1 057 deaths occurred during the follow-up period. Taking patients with duration of sleep as 7 h/d for reference, the multivariate adjusted hazard ratios (95%CI) of all-cause mortality appeared as ≤6, 8, 9 and ≥10 h/d were 1.14 (0.94-1.37), 1.10 (0.91-1.32), 1.33 (1.05-1.70), and 1.52 (1.24-1.87), respectively which were associated with the duration of sleep. Data from the subgroup analysis showed that this was consistent with the whole population. Longer duration of sleep was associated with the all-cause mortality but no significant association was found between shorter duration of sleep and the all-cause mortality.
Conclusion:Longer duration of sleep seemed to have increased the risk of all-cause mortality in type 2 diabetic patients.