Research progress in enterovirus D68
10.3760/cma.j.issn.1003-9279.2019.04.023
- VernacularTitle: 肠道病毒D68的研究进展
- Author:
Yafang HU
1
;
Runan ZHU
Author Information
1. Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing 100020, China
- Publication Type:Review
- Keywords:
Enterovirus D68;
Biological characteristics;
Clinical features;
Epidemiology
- From:
Chinese Journal of Experimental and Clinical Virology
2019;33(4):440-443
- CountryChina
- Language:Chinese
-
Abstract:
Enterovirus D68 (EV-D68) was first isolated in 1962, and then reported infrequently. As its genetic diversity increased rapidly, the detection rate of EV-D68 has been rising worldwide in recent decade. Since EV-D68 caused the most widespread outbreak in the United States, Canada and Europe in 2014, an increasing number of studies had reported that EV-D68 was associated with severe respiratory diseases and neurological complications, even death. However, the pathogenesis of EV-D68 remains unclear. Moreover, no vaccines or specific antiviral agents are available for prevention and treatment for EV-D68 infection at present. Therefore, continued surveillance and rapid diagnosis of EV-D68 infection will be beneficial to prevent and manage the potential outbreak. This article gives an overview of the biological characteristics, clinical features, and epidemiology of EV-D68.
