Analysis of human papillomavirus infection characteristics and genotypes in Shenyang area of Liaoning province
10.3760/cma.j.issn.1003-9279.2019.04.012
- VernacularTitle: 辽宁省沈阳地区女性人乳头瘤病毒感染及基因分型情况分析
- Author:
Te QI
1
;
Yujing HUANG
;
Chao LIU
;
Bo WANG
;
Hao WU
;
Ye MIAO
;
Qiang RUAN
Author Information
1. Virology Laboratory, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Journal Article
- Keywords:
Human papillomavirus;
Genotype;
Infection characteristics
- From:
Chinese Journal of Experimental and Clinical Virology
2019;33(4):389-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the distribution of human papillomavirus (HPV) infection characteristics and genotypes in Shenyang area of Liaoning province.
Methods:HPV genes were detected in cervical exfoliated cells from 55, 548 patients by amplification and diversion hybridization.
Results:A total of 9, 566 patients were positive for HPV infection with a positive rate of 17.22%. Additionally, the positive rate of high risk HPV infection was 14.57% and the positive rate of single genotype HPV infection was 13.63%. Totally, 12, 360 HPV viruses were detected. Among them, 10, 879 HPV viruses were classified into high risk genotypes (10, 879 out of 12, 360, 88.02%). The genotypes in women with ages less than 20 were 16/11/6/51/58/52 genotypes; the susceptible HPV genotypes in other women were 16/58/52/53/39/51/81 genotypes.
Conclusions:HPV infections in Shenyang are mainly infections with high risk viruses and single infection. The infection rate and genotype distribution of HPV are different in different age groups. More suitable HPV vaccine prophylaxis can be taken according to the epidemic characteristics of HPV in this area.
