Advances in the research of sensory nerve regeneration in tissue engineering skin
10.3760/cma.j.issn.1009-2587.2019.03.016
- VernacularTitle: 组织工程皮肤中感觉神经再生的研究进展
- Author:
Zhikang ZHU
1
;
Pan WU
;
Xingang WANG
;
Chunmao HAN
Author Information
1. Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
- Publication Type:Review
- Keywords:
Tissue engineering;
Skin;
Nerve regeneration;
Neurturin;
Hair follicle;
Dermal scaffold
- From:
Chinese Journal of Burns
2019;35(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Severe skin damage not only causes a mass of tissue defect, but also leads to the loss of various sensory functions. Tissue engineering skin provides a new way for high-quality wound repair, while there are still many problems in the recovery of sensory function, such as abnormality or loss of sensation of pain, touch, and temperature. Therefore, when tissue engineering skin is used to promote wound healing, regeneration and functional recovery of sensory nerve have attracted more and more attention. This article introduces the kind, distribution, regeneration, and factors influencing regeneration of sensory nerve in skin, and explores strategies in promoting regeneration of sensory nerve from dermal scaffold, seed cell, and neurturin of tissue engineering skin.