Survival analysis of people living with HIV/AIDS in Sichuan province, 1991-2017
10.3760/cma.j.issn.0254-6450.2019.03.010
- VernacularTitle: 四川省1991－2017年HIV/AIDS生存分析
- Author:
Yali ZENG
1
;
Houlin TANG
2
;
Jumei LI
1
;
Qiushi WANG
1
;
Hang YU
1
;
Ling SU
1
;
Wei YANG
1
;
Yi GONG
1
;
Tian LI
1
;
Wanli HUANG
1
;
Linglin ZHANG
1
;
Wenhong LAI
1
Author Information
1. Department of AIDS/STD Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China
2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
- Publication Type:Journal Article
- Keywords:
HIV/AIDS;
Retrospective study;
Survival analysis
- From:Chinese Journal of Epidemiology
2019;40(3):309-314
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the survival time of people living with HIV/AIDS and related influencing factors in Sichuan province during 1991-2017.
Methods:A retrospective cohort study was conducted to analyze the data of 143 988 HIV/AIDS cases. The data were collected from Chinese HIV/AIDS Comprehensive Information Management System. Life table method was used to calculate the survival proportion of the cases, and Cox proportion hazard regression model was used to identify the factors related with survival time.
Results:Among 143 988 HIV/AIDS cases a total of 30 420 cases died of AIDS related diseases (21.1%) and the average survival time was 11.51 years (95%CI: 11.39-11.64). Multivariate Cox regression analysis showed that the influencing factors for the survival of HIV/AIDS cases were gender (male vs. female, HR=1.35, 95%CI: 1.32-1.40), education level (primary school or below vs. junior middle school: HR=1.15, 95%CI: 1.12-1.18), ethnic group (Han vs. other ethnic groups, HR=1.46, 95%CI: 1.41-1.52), occupation (farmer vs. other occupations: HR=1.26, 95%CI: 1.22-1.29), age (≥55 years old vs. 15-24 years old: HR=3.18, 95%CI: 3.02- 3.36), disease phase (AIDS vs. HIV infection: HR=1.44, 95%CI: 1.39-1.48), antiretroviral therapy (ART) (receiving ART vs. receiving no ART: HR=0.20, 95%CI: 0.19-0.20), and CD4+T cell counts at diagnosis (>500 cells/μl vs.<200 cells/μl: HR=0.42, 95%CI: 0.40-0.45).
Conclusions:The average survival time of HIV/AIDS cases was 11.51 years in Sichuan during 1991- 2017. The risk factors for the survival of the cases were male, education level of primary school or below, Han ethnic group, farmer, old age at diagnosis, disease phase, The protective factors for the survival of HIV/AIDS cases were receiving ART and higher CD4+ T cell counts at diagnosis.
