Treatment of syndromic craniosynostosis with distraction osteogenesis
10.3760/cma.j.issn.1009-4598.2019.03.008
- VernacularTitle: 牵张成骨术治疗婴幼儿综合征型颅缝早闭症
- Author:
Haini CHEN
1
;
Weimin SHEN
;
Yi JI
;
Jianbing CHEN
;
Jie CUI
Author Information
1. Department of Burn and Plastic Surgery, Children′s Hospital of Nanjing Medical University, Nanjing 210008, China
- Publication Type:Clinical Trail
- Keywords:
Osteogenesis, distraction;
Cranial flap;
Craniosynostosis;
Syndrome
- From:
Chinese Journal of Plastic Surgery
2019;35(3):254-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of distraction osteogenesis in the treatment of syndromic craniosynostosis.
Methods:The clinical data of 6 children with syndromic craniosynostosis from January 2014 to September 2018 were retrospectively analyzed. There were 5 males and 1 female, aged from 1 month and 21 days to 6 years and 1 month, with an average age of 30 months. There were 3 Crouzon syndrome, 1 Pfeiffer syndrome, 1 Vogt syndrome (ACS Ⅱ) and 1 Clove leaf skull syndrome. The distraction osteogenesis apparatus was used in this procedure. The distraction osteogenesis was prolonged twice a day, 0.4 mm each time, and the prolongation was stopped when the skull shape was significantly improved. Three-dimensional CT scans of the skull were reviewed after 6 months, suggesting that distraction osteogenesis was good, then the lengthener was removed. Complications were recorded, and extended distances were measured. Cranial indices before and after operation were compared to evaluate the efficacy, safety and feasibility of the operation.
Results:The procedure of operation and traction was successful in all 6 children. There were no complications such as cranial spinal fluid (CSF) leakage or intracranial infection occurred. The increased distance was (19.1±3.3) mm, ranging from 15.2 to 25.6 mm. The preoperative cranial index was 89.6 ±7.3, while the postoperative cranial index was 74.2 ±3.6. All patients were followed up from 3 to 20 months, with the average of 14 months. The posterior cranial flatness was improved, and the patients were satisfied with the surgical results.
Conclusions:Distraction osteogenesis is effective and reliable in treating the premature fusion of cranial suture, and it produces excellent result with low rate of CSF leak and infection.
