Detection and surveillance of west nile virus infection in southern Xinjiang, China, 2012
10.3760/cma.j.issn.1003-9279.2019.03.010
- VernacularTitle: 新疆南部地区2012年西尼罗病毒感染的检测与监测
- Author:
Shihong FU
1
;
Lei CAO
;
Zhi LYU
;
Ying HE
;
Wenwen LEI
;
Fan LI
;
Huanyu WANG
;
Guodong LIANG
Author Information
1. National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
- Publication Type:Journal Article
- Keywords:
West Nile virus;
Infection;
Detection
- From:
Chinese Journal of Experimental and Clinical Virology
2019;33(3):271-274
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the west nile virus (WNV) infection in Xinjiang, China.
Methods:Serum samples were collected from patients with fever and chicken in southern Xinjiang, 2012. The presence of WNV-specific immunoglobulin M (IgM) antibodies and neutralizing antibodies was examined through enzyme-linked immunosorbent assay (ELISA) and plaque reduction neutraization test (PRNT90).
Results:A total of 1 712 serum samples of outpatients and inpatients were collected in 8 counties in southern Xinjiang. As a result , 22 samples were positive for WNV IgM antibody and 48 samples were positive for WNV neutralization antibody, among which 21 WNV IgM antibody positive samples and 42 WNV neutralization antibody positive samples were from Jiashi county. Of 383 chicken serum samples collected in 4 counties in southern Xinjiang, only 28 samples were positive for WNV neutralizing antibody, interestingly, all positive chicken serum samples were collected from Jiashi county.
Conclusions:This study revealed that WNV infection occurred in human and poultry in southern Xinjiang, 2012, mainly in Jiashi county.
