Clinical study on traditional Chinese medicine syndrome differentiation and treatment of pneumoconiosis
10.3760/cma.j.issn.1001-9391.2019.03.005
- VernacularTitle: 中医辨证论治治疗尘肺病的临床研究
- Author:
Pingping SONG
1
;
Juan LIU
;
Hua XIAO
;
Xueyu MA
;
Songquan ZHANG
;
Yanxia CHEN
Author Information
1. Qingdao Central Hospital, Qingdao 266042, China
- Publication Type:Case Reports
- Keywords:
Pneumoconiosis;
TCM syndrome differentiation;
Quality of life questionnaire;
C-reactive protein
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2019;37(3):186-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical effect of traditional Chinese medicine (TCM) syndrome differentiation in the treatment of pneumoconiosis.
Methods:We selected 160 pneumoconiosis patients who were hospitalized in our hospital from July 2015 to July 2016. 102 patients were divided into experimental groups, and the other 58 patients were assigned to the control group. These patients were randomly assigned. The control group was given routine treatment, while the experimental group received conventional treatment combined with TCM syndrome differentiation. We rated patients' quality of life using the SF-36 Quality of Life Scale. C-reactive protein levels in both groups before and after treatment were detected by ELISA. Furthermore, we detected the expression levels of IL-6 mRNA and TGF-β mRNA in serum before and after treatment by RT-PCR.The analysis was performed with SPSS19.0 software. The normal distribution measurement data was expressed by Mean±SD, and the t-test was used for statistical analysis. Non-normal distribution measurement data were expressed as median(M) and interquartile range (P25, P75), and non-parametric test was used for statistical analysis.
Results:Compared with the control group, the readmission rate in the experimental group decreased within 3 months; The SF-36 quality of life score results of the two groups showed a statistically significant difference in BP, VT and RE (P<0.05);The levelofCRPdecreasedsignificantlyafter treatment in bothgroups,and thedifferencewasstatistically significant (P<0.05).Comparedwith thecontrolgroup, the levelsofIL-6mRNAandTGF-β1mRNA alsodecreased (P<0.05).
Conclusion:TCM syndromedifferentiation and treatmentofpneumoconiosis can effectively improve the patient's condition and life quality. We predict that it may inhibit the progression of pulmonary fibrosis in pneumoconiosis.
