Clinical analysis of 22 cases of syndrome caused by acute poisoning
10.3760/cma.j.issn.1001-9391.2019.02.012
- VernacularTitle: 急性中毒致横纹肌溶解综合征22例临床分析
- Author:
Yixu WU
1
;
Guangju ZHAO
;
Guangliang HONG
;
Mengfang LI
;
Dong LI
;
Bin WU
;
Qiaomeng QIU
;
Zhongqiu LU
Author Information
1. The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
- Publication Type:Journal Article
- Keywords:
Poisoning;
Rhabdomyolysis;
Fluid resuscitation;
Blood purification
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2019;37(2):136-138
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics, treatment and prognosis of rhabdomyolysis (RM) caused by acute poisoning.Summarize the clinical characteristics and treatment experience, pay attention to the complications and improve the quality of rescue.
Methods:We collecte and summarize the clinical data, treatment and prognosis of 22 cases of RM caused by acute poisoning.
Results:We found that 21 patients (95.5%) had muscle damage, 13(59.1%) with coma, 8(36.4%) with brown, tea or even soy sauce urine, 6(27.3%) had acute renal injury (AKI), and 4(18.2%) had multiple organ dysfunction syndrome (MODS). After the treatment, 21 cases (95.5%) got better, and one case were discharged. All the patients with AKI were survived, three of them were treated by hemodialysis, and the other recovered gradually after massive fluid replacement.
Conclusion:Acute poisoning combined with RM is not uncommon in clinic. We should pay attention to examination of serum enzymes and other indicators, observe the clinical symptoms and make early diagnosis. The key to diagnosis and treatment is early fluid resuscitation, comprehensive treatment, blood purification and maintain the stability of water and electrolyte.
