Effect of long-term low-concentration mixed benzene exposure on male peripheral blood in an automobile manufacturing enterprise
10.3760/cma.j.issn.1001-9391.2019.02.007
- VernacularTitle: 某汽车制造企业长期低浓度混苯接触对男性外周血的影响
- Author:
Yanru LI
1
;
Chunjiao XIE
;
Congxi QIU
;
Qiuyue LIN
;
Yimin LIU
Author Information
1. Guangzhou Occupational Disease Prevention and Treatment Hospital, Guangzhou 510620, China
- Publication Type:Case Reports
- Keywords:
Benzene;
Blood system;
Male;
Low concentration
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2019;37(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigated the effect of long-term low-concentration mixed benzene exposure on peripheral blood of male workers.
Methods:A case-control study was conducted to select 452 male workers exposed to mixed benzene (benzene, toluene, xylene) for five consecutive years from January 2012 to December 2016 in an automobile manufacturer as case group, and 438 male administrative and logistic managers who underwent physical examination during the same period as control group. The peripheral blood of the two groups was tested and compared, and the occupational hazards in the workplace were detected.
Results:There were low dose exposure to mixed benzene in the enterprise, but the test results met the occupational exposure limit requirements. During the five years from 2010 to 2016, between the two groups of workers, the mean values of WBC, NEUT, RBC and Hb were statistically different (P<0.05). There was no statistical difference (P>0.05) in the mean value of PLT. The abnormal rate of main peripheral blood indexes in the control group was higher than that in the exposed group. There were significant differences in NEUT, RBC and Hb (P< 0.05), but no significant differences in WBC and PLT (P>0.05).
Conclusion:It can not be concluded that long-term low-concentration mixed benzene exposure can cause the change of peripheral blood index.