Research progresson decellularized adipose tissue extracellular matrixscaffolds
10.3760/cma.j.issn.1009-4598.2019.01.020
- VernacularTitle: 脱细胞脂肪组织基质材料研究进展
- Author:
Xiao GUO
1
;
Ang ZENG
;
Lin ZHU
Author Information
1. Department of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100032, China
- Publication Type:Review
- Keywords:
Extra cellular matrix;
Decellularized adipose tissue;
Scaffolds;
Tissue engineering
- From:
Chinese Journal of Plastic Surgery
2019;35(1):89-92
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular matrix plays an important role in cell proliferation, differentiation and gene expression. It is similar to the three-dimensional structure of native tissue, which has been widely used in tissue engineering as a scaffold. Decellularized adipose tissue matrix is derived from adipose tissue, which is abundant and easily obtainable.It alsohas the function of promoting adipogenesis and angiogenesis. It provides a good microenvironment for adipose derived stem cells, and has great potential for the repair and reconstruction of soft tissue defects.In this paper, the preparation methods, the effects of the different forms and applications of decellularized adipose extracellular matrix scaffolds are reviewed.
