An experimental study of Zn/Ca/P-containing coatings on titanium implant surface modified by plasma electrolytic oxidation
10.3760/cma.j.issn.1002-0098.2019.01.009
- VernacularTitle: 含锌钙磷涂层种植体成骨性能的动物实验
- Author:
Wei FENG
1
;
Baohong ZHAO
2
;
Wei ZHANG
3
;
Zeng LIN
4
Author Information
1. Department of Stomatology, Affiliated Hospital of Jining Medical University, Jining 272000, China
2. Center of Implant Dentistry, School of Stomatology, China Medical University & Liaoning Institute of Dental Research, Shenyang 110002, China
3. Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China
4. School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110004, China
- Publication Type:Journal Article
- Keywords:
Zinc;
Dental implants;
Osseointegration;
Plasma electrolytic oxidation
- From:
Chinese Journal of Stomatology
2019;54(1):46-51
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the osteogenic activity of Zn/Ca/P-containing coatings on titanium implant surface modified by plasma electrolytic oxidation (PEO).
Methods:Three groups implants including Zn/Ca/P-containing surface treated by PEO in experimental groups and Ca/P-containing and TiO2 sandblasted surface in control group were randomly inserted in the bilateral mandibular of rabbits. Mechanical testing and implant-bone interface observation were performed at 4, 6, 8, 10 and 12 weeks after implantion.
Results:Zn/Ca/P-containing coating presented a microporous structure. The push-out value indicated the statistical differences among the three groups at each observed time point (P<0.05), and implant-bone bonding power reached a maximum value at 12 weeks, those in the Zn/Ca/P-containing group [(1.57±0.26) MPa] was higher than those in the group with sandblasted surface [(0.83±0.24) MPa] (P<0.05). Histological examination and implant-bone interface observation using field scaning electron microscope (FSEM) showed that the new bone of implant-bone interface increased with healing time and the result from Zn/Ca/P-containing group was superior to that from the control groups at each observed time point.
Conclusions:Zn/Ca/P-containing coatings by PEO can accelerate bone formation and remodeling, and enhance bone-implant bonding force.
