The Role of Lubricin in Wound Repair of Musculoskeletal System
10.16156/j.1004-7220.2020.01.22
- VernacularTitle:润滑素在肌骨系统损伤修复中的作用
- Author:
Zhongjie DING
1
;
Yan XIANG
2
;
Qing LUO
1
Author Information
1. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University
2. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University；Department of Criminal Science and Technology, Chongqing Police College
- Publication Type:Journal Article
- Keywords:
lubricin;
musculoskeletal system;
tissue injury;
tissue repair
- From:
Journal of Medical Biomechanics
2020;35(1):E114-E119
- CountryChina
- Language:Chinese
-
Abstract:
Lubricin is widely expressed in tissues in the musculoskeletal system, including articulate cartilage, tendon and synovium, which shows a close relationship with the structure and pathology of these tissues. Lubricin plays an important role in lubrication, anti-adhesion, proliferation inhibition and inflammation regulation, which may facilitate the healing of impaired tissues in the musculoskeletal system. This article reviews the research progress on expression and regulation of lubricin as well as its structure and function in wound repair of the musculoskeletal system, so as to provide theoretical evidences for further researches on the role of lubricin in the musculoskeletal system with its related mechanisms and the clinical application of lubricin.
