Mechanostat of bone remodelling under dynamic loads
10.3871/j.1004-7220.2015.04.346
- VernacularTitle:动载荷作用下骨重建力学调控机制
- Author:
Zong-min MA
1
;
Shu-xian LI
2
Author Information
1. Institute of Biomedical Engineering, Dalian University
2. Mechanical Engineering College, Dalian University
- Publication Type:Journal Article
- Keywords:
Bone remodelling;
Mechanostat;
Dynamic load;
Fatigue
- From:
Journal of Medical Biomechanics
2015;30(4):E346-E349
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the mechanostat of bone remodeling under dynamic loads. Methods By analysis on mechanostat of bone remodeling and absorption from the idea of mechanical fatigue strength theory, the mechanostat of bone remodeling under dynamic loads was developed. Damage was selected as the mechanical stimulus under dynamic loads and the model of bone remodeling under dynamic loads was proposed. Physical exercise for prevention and treatment of osteoporosis was simulated to analyze the biomechanical phenomenon why the osteogenesis effect under dynamic loads seems better than that under static loads. Results The biomechanical phenomenon as mentioned above was reasonably explained. An increase of 10%-30% in physical exercise could cause an increase of 3.13%-8.61% in bone mineral density. Conclusions The mechanostat of bone remodeling under dynamic loads will provide theoretical guidance for using mechanical vibration to treat or prevent diseases related to bone metabolism, which is the supplement and improvement for mechanostat of bone remodeling.
