Development of ultrasonic viscoelasticity detection system by shear wave dispersion ultrasound vibration
- VernacularTitle:基于剪切波频散超声振动的黏弹性检测系统开发
- Author:
Yan-rong GUO
1
;
Hao-ming LIN
1
;
Ying ZHU
1
;
Yuan-yuan SHEN
1
;
Yi ZHENG
2
;
Tian-fu WANG
1
;
Si-ping CHEN
1
;
Xin CHEN
1
Author Information
1. National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University
2. Department of Electrical and Computer Engineering, St. Cloud State University
- Publication Type:Journal Article
- Keywords:
Viscoelasticity;
Shear wave dispersion ultrasound vibration (SDUV);
Acoustic radiation force;
Harmonic vibration;
Liver fibrosis
- From:
Journal of Medical Biomechanics
2014;29(2):E174-E179
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an ultrasonic viscoelastic detection system to measure the viscoelasticity of in vitro tissues. Methods Based on the method of shear wave dispersion ultrasound vibration (SDUV), this system applied acoustic radiation force to excite harmonic vibration in soft tissues. The propagation of shear waves induced by the vibration was detected and the tissue viscoelasticity properties were calculated. The standard phantom and rat liver experiment were conducted using this system, and preliminary assessment of the system was completed. Results The measured result of standard phantom was close to the calibration value. The viscous and elastic coefficient of rat liver were (1.12±0.41) Pa•s and (0.81±0.40) kPa, respectively. Conclusions The results about the standard phantom and rat liver experiment approved feasibility of the system for viscoelasticity measurement on in vitro animal experiment, which is a preliminary exploration for the realization of liver fibrosis detection of human body.