Technical advances in space cell bioreactor
- VernacularTitle:空间细胞生物反应器技术研究进展
- Author:
Bing SHANGGUAN
1
,
2
;
Shu-jin SUN
2
;
Yu-xin GAO
2
;
Wen-sheng HOU
1
;
Mian LONG
2
Author Information
1. Bioengineering College of Chongqing University
2. Key Laboratory of Microgravity, Center of Biomechanics and Bioengineering, Institute of Mechanics, Chinese Academy of Sciences
- Publication Type:Journal Article
- Keywords:
Space bioreactor;
Microgravity;
Microfluidic technique;
Parametric control;
Microscopic imaging
- From:
Journal of Medical Biomechanics
2014;29(6):E582-E588
- CountryChina
- Language:Chinese
-
Abstract:
Cell biology experiments in space are indispensable for investigating the effects of microgravity environment on living organisms. As an important technological means of supporting life science researche, space cell bioreactor may directly influence the data quality of space cell biology experiments and research level. To date, space cell bioreactor techniques are still under development, and lack of standard rationale. In this article, the technical progresses of space cell bioreactor were reviewed, by introducing the operational principle of several typical space cell bioreactors, analyzing the mode of culture medium supplying and character of fluid mechanics environment in space, as well as the relevant supporting techniques about the parametric controlling on temperature, dissolved oxygen and pH value and on-line microscopic imaging, so as to discuss the future perspective about space cell bioreactor techniques.
