Research on pressure-volume relations for the rabbit eye in vivo
- VernacularTitle:在体兔眼压强-体积关系的实验研究
- Author:
Kun-ya ZHANG
1
;
Qian-qian CUI
1
;
Xiu-qing QIAN
1
;
Hai-ying QUAN
1
;
Zhi-cheng LIU
1
Author Information
1. School of Biomedical Engineering, Capital Medical University
- Publication Type:Journal Article
- Keywords:
Rabbit eye in vivo;
Pressure volume relationship;
Mechanical properties;
Ocular rigidity
- From:
Journal of Medical Biomechanics
2011;26(2):E137-E141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To obtain pressure-volume relatioship for the rabbit eye in vivo. Method Physiological salt solution was injected with the rate of 20 μL/min through the limbus to the anterior chamber of the rabbit eye for 100 min and the intraocular pressure (IOP) was recorded. Results The relationship between IOP and injection time could be fitted to a segmented function with a characteristic point called IOPg. The ocular rigidity coefficients before and after this IOPg were (4.02±0.86) mmH2O/μL and (2.43±0.94) mmH2O/μL, respectively (1 mmH2O=9.8 Pa), showing significant difference. Conclusions IOPg existed in all curves of IOP and injection time and the ocular rigidity coefficients were dependent on the injection rate and position of IOPg. Parameters of the fit function between IOP and injection time have definite physiological significance.
