Effect of Isolation Policy Using Cohorting Rooms on Isolation Rate of Multidrug-resistant Organisms and Antimicrobial Use Density: Focusing on Methicillin-Resistant Staphylococcus aureus and Multidrug-resistant Acinetobacter baumannii.
10.14192/kjnic.2013.18.1.1
- Author:
Mi Hui BAK
;
Oh Hyun CHO
;
Eun Hwa BAEK
;
Sunjoo KIM
;
In Gyu BAE
- Publication Type:Original Article
- Keywords:
Acinetobacter baumannii;
Drug resistance;
Methicillin-Resistant Staphylococcus aureus;
Multiple;
Patient Isolation
- MeSH:
Acinetobacter;
Acinetobacter baumannii;
Carbapenems;
Cohort Studies;
Colon;
Drug Resistance;
Glycopeptides;
Humans;
Methicillin Resistance;
Methicillin-Resistant Staphylococcus aureus;
Patient Isolation;
Patients' Rooms;
Prospective Studies
- From:Korean Journal of Nosocomial Infection Control
2013;18(1):1-6
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: We evaluated the effectiveness of isolation measures using cohorting rooms and antimicrobial use in reducing the isolation rate of methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Acinetobacter baumannii (MDR-AB). METHODS: Four cohorting rooms (16 beds) for patients colonized or infected with multidrug-resistant organisms (MDRO) have been created in the general wards of our 894-bed hospital since October 2003. We prospectively evaluated the isolation rates of MRSA and MDR-AB, and amount of antimicrobial use during the 8-year study period. We also investigated the relationship between antimicrobial use density (AUD) and the isolation rates of MRSA and MDR-AB. RESULTS: After creating cohorting rooms, the isolation rates of MRSA decreased from 1.56 cases per 1,000 patient-days from 2004-2005 to 1.24 from 2006-2007 (P=0.57). The isolation rates of MDR-AB also decreased from 0.72 from 2004-2005 to 0.36 from 2010-2011 (P<0.01). The mean quarterly AUDs of glycopeptides and carbapenems were 30.17+/-6.80 and 19.5+/-7.10, respectively. There were no significant correlations between AUD values and the isolation rate of MRSA or MDR-AB. CONCLUSION: This study suggests that isolation measures using cohorting rooms to help limit the transmission of MDRO infection and colonization, especially MDR-AB, in resource-limited settings is feasible and efficacious.
