Clinical application of the swirling flow mechanism in arterial prostheses and bypasses
- VernacularTitle:动脉血流旋动原理在人造血管研制和血管移植术中的应用
- Author:
Xiao LIU
1
;
An qiang SUN
1
;
Fan ZHAN
1
;
Zeng sheng CHEN
1
;
Xiao yan DENG
1
Author Information
1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University
- Publication Type:Journal Article
- Keywords:
Swirling flow;
Computational fluid dynamics(CFD);
Shear stress;
Flow field
- From:
Journal of Medical Biomechanics
2010;25(5):E334-E337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To apply the swirling flow mechanism to the design of arterial prostheses with small diameters and the arterial bypass surgery to resolve the acute thrombus in small diameter prostheses after implantation, and lessen the restenosis of bypassed arteries due to the formation of internal hyperplasia. Method The computational fluid dynamics (CFD) method was used to investigate the flow field and wall shear stress distribution of a new graft, an S type bypass and an axis deviated arterial bypass, which all had the swirling flow. In addition, the platelet adhesion under swirling flow and internal hyperplasia in S-type bypass were measured. Results The swirling flow can apparently enhance the wall shear stress (WSS) and suppress the platelet adhesion and internal hyperplasia. Conclusions The swirling flow can significantly improve the flow field in arterial graft and bypass to inhibit the acute thrombus in small diameter prostheses and internal hyperplasia after bypass surgery.
