Effects of nutritional interventions based on nutritional risk assessment strategies on nutritional status and liver function in patients with cirrhosis
10.3760/cma.j.issn.1672-7088.2019.33.004
- VernacularTitle: 基于营养风险评估策略下的营养干预对肝硬化患者营养状况及肝功能的影响
- Author:
Xiaolan ZOU
1
;
Jianhong WEI
Author Information
1. Department of Gastroenterology, Wuxi People′s Hospital, Jiangsu Province, Wuxi 214023, China
- Publication Type:Clinical Trail
- Keywords:
Cirrhosis;
Nutritional risk;
Nutritional intervention;
Nutritional indicators;
Liver function
- From:
Chinese Journal of Practical Nursing
2019;35(33):2575-2579
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of nutritional interventions based on nutritional risk assessment strategies on nutritional status and liver function in patients with cirrhosis.
Methods:Totally126 patients with cirrhosis admitted from July 2016 to October 2017 were enrolled. The prospective study was used and the patients were randomly divided into the treatment group and the control group with 63 cases in each group. The control group received routine nursing intervention, while the treatment group was combined nutritional intervention based on the nutritional risk assessment strategy. After 3 months of follow-up, serum nutrition indicators, liver function, and complications were compared between the two groups.
Results:The serum albumin, prealbumin and transferrin levels in the treatment group were (42.36±5.24) g/L, (0.37±0.08) g/L, and (3.01±0.42) g/L, which were significantly higher than those in the control group, which were (34.24±5.36) g/L, (0.30±0.07) g/L, (2.65±0.52) g/L (t=8.598, 5.227, 4.275, P<0.05 or 0.01); serum alanine aminotransferase and total bilirubin content were (95.32±12.45) μmol/L, (272.36±30.12) μmol/L, which were significantly lower than those of the control group [(114.21±13.20) μmol/L, (320.42±41.52) μmol/L]. The prothrombin time [(14.36±1.32) s] was significantly shorter than that of the control group [(16.12±1.20) s] (t=8.263, 7.437, 7.831, P<0.05); the complication rate of the treatment group was 7.94% (5/63), which was significantly lower than that of the control group (22.22%) (14/63)(χ2=5.020, P<0.05).
Conclusions:Nutrition intervention based on nutritional risk assessment strategy can improve nutritional status, relieve liver damage and reduce the incidence of complications such as peritonitis in liver cirrhosis patients.
