Application and effect evaluation of clohexidine wipes in patients with liver transplantation
10.3760/cma.j.issn.1672-7088.2019.32.013
- VernacularTitle: 氯己定湿巾在肝移植术后患者擦浴中的应用及效果评价
- Author:
Mingrong GAO
1
;
Liqiong LI
1
;
Yujun TANG
1
;
Shouzhen CHENG
1
Author Information
1. Department of ICU, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
- Publication Type:Clinical Trail
- Keywords:
Clohexidine;
Clean bath;
Liver transplantation;
Intensive care;
Infection
- From:
Chinese Journal of Practical Nursing
2019;35(32):2543-2547
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the application of clohexidine wipes in patients after liver transplantation and the effect of infection prevention.
Methods:A total of 279 patients who received orthotopic liver transplantation in the first affiliated hospital of sun yat-sen university from January 2017 to December 2018 and were transferred to the intensive care department of our hospital after the surgery were selected as subjects. Among them, 145 patients who received liver transplantation between January and December 2017 were selected as the control group. From January to December, 2018, 134 patients after liver transplantation were enrolled as the intervention group, and were treated with clohexidine 2% gluconate wet wipes, and the hospital infection rate, infection rate, multiple drug-resistant bacteria infection rate, bath time consumption, and adverse reaction rate were compared between the two groups.
Results:The hospital infection rate of the control group was 20.00% (29/145), the infection rate of patients was 37.93%(55/145), the infection rate of multiple drug-resistant bacteria was 25.52%(37/145), and the infection rate of the intervention group was 11.19% (15/134), 24.63% (33/134), 14.93% (20/134). The differences were statistically significant (χ2=4.065, 5.709, 4.806, P<0.05). The bath time of the control group was (16.70±1.42) minutes, and the intervention group was (14.07±1.53) minutes. Compared with the control group, the bath time of the intervention group was saved, and the difference was statistically significant (t=9.637, P<0.01).No discomfort symptoms such as disinfectant allergy were found in both groups.
Conclusion:The application of clohexidine 2% gluconate wet wipes in the wiping bath of patients after liver transplantation had a good effect, significantly reducing the hospital infection rate, saving the time of wiping bath.
