Cognitive behavior group intervention on the depression of patients with acute leukemia
10.3760/cma.j.issn.1672-7088.2019.28.003
- VernacularTitle: 认知-行为治疗干预对急性白血病患者抑郁情绪的影响
- Author:
Yang HE
1
;
Yingcheng ZHANG
;
Lianying XU
Author Information
1. Department of Hematology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
- Publication Type:Journal Article
- Keywords:
Nurses;
Cognitive-behavioral therapy;
Acute leukemia;
Depression
- From:
Chinese Journal of Practical Nursing
2019;35(28):2170-2174
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of cognitive behavioural therapy (CBT), which is dominated by nurses, on depression in patients with acute leukemia.
Methods:Patients with acute leukemia admitted to the Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine were evaluated with a rapid depressive symptom (QIDS-SR16) self-rating scale. Patients with a score higher than 11 were psychiatrists from the Shanghai Mental Health Center. Interviews and Hamilton Depression Rating (HAMD-17) assessment and clinical stereotype examination (SCID-I) diagnostic screening were performed. Patients with significant depressive symptoms who met the inclusion criteria were included (without considering DSM-5 diagnosis for depressive disorder). The computer random number method was assigned to the control group (group C), the therapist-led group CBT group (group T), the group CBT group with the nurse as the main body and therapists as the supervisors (group N). The group C was given the conventional method and the group T and N was given the standardized group CBT once a week for 8 weeks. Interviews were performed at baseline (before intervention), 4 weeks, and 8 weekends to assess the HAMD scale score.
Results:Finally, 90 patients were enrolled, 30 in each group. At the end of the 4th week, the HAMD scale score (22.60±2.71) in the group T was lower than that before the intervention (25.77±2.93), and lower than the group N (24.57±2.82) and the group C (25.90± 3.88), the difference was statistically significant (t=5.395, 7.473, P<0.01 or 0.05). At the end of the 8th week, the group T (21.00±2.18) and the group N had a HAMD scale score (19.30±2.45) lower than the pre-intervention (25.77±2.93, 25.90±3.26), and were lower than the group C (24.80±3.56), the difference was statistically significant (t=6.192, 7.323, P<0.05 or 0.01).
Conclusions:CBT can improve the anxiety and depressive symptoms of patients with acute leukemia, and it is worthy of popularization and application.
