Nursing experience in the process of diagnosing and treating post-transplantation lymphoproliferative disorder
10.3760/cma.j.issn.1672-7088.2019.27.009
- VernacularTitle: 儿童肝移植术后淋巴细胞增生性疾病诊疗过程的护理
- Author:
Mingzhu HUANG
1
;
Yefeng LU
;
Ying LU
;
Qinzhi HU
Author Information
1. Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai 200127, China
- Publication Type:Clinical Trail
- Keywords:
Nursing care;
Post-transplantation lymphoproliferative disorder;
Pediatric liver transplantation;
Rituximab;
Epstein-Barr virus
- From:
Chinese Journal of Practical Nursing
2019;35(27):2124-2128
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the key points of nursing in the process of diagnosing and treating the common complication--- post-transplantation lymphoproliferative disorder (PTLD) after pediatric liver transplantation.
Methods:The clinical data of 21 children with PTLD after liver transplantation. The key point of nursing in the process of prevention, onset, diagnosis and treatment was summarized.
Results:With the individual and combined treatments 18 patients gained remission except for 1 patient died because of perforation and sequent intractable haemorrhage and 2 patient died for the development of lymphoma. In terms of nursing, during the prevention stage, it is critical to insist the regular follow-up to make early diagnosis. More efforts should be made to obtain the children′s cooperation to complete the examination. During the infusion of rituximab, strengthened monitoring is necessary and more attention should be paid to the special nursing when other complications such as intractable haemorrhage, intestinal obstruction or perforation occurs.
Conclusions:The nursing care of PTLD is complicated. Individual and careful nursing regimens should be made based on the specific situations in different stages.
