Analysis of the effect of pregnancy complicated with acute pancreatitis on maternal and infant outcomes
10.3760/cma.j.issn.1008-6706.2019.24.009
- VernacularTitle: 妊娠合并急性胰腺炎对母婴结局的影响
- Author:
Renmei XU
1
;
Yongming BAI
2
;
Wuhua TONG
1
Author Information
1. Department of Intensive Care Unit, the Maternal and Child Health Care Hospital of Jiaxing, Jiaxing, Zhejiang 314000, China
2. Department of Internal Medicine, Wangdian People's Hospital of Jiaxing, Jiaxing, Zhejiang 314011, China
- Publication Type:Journal Article
- Keywords:
Pregnancy outcome;
Pancreatitis;
Infant, premature;
Pregnancy complications;
Respiratory distress syndrome, newborn
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(24):2976-2979
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of pregnancy with acute pancreatitis on maternal and infant outcomes, thus to provide reference for the development of clinical intervention programs.
Methods:From January 2012 to January 2018, 62 pregnant patients with acute pancreatitis in the Maternal and Child Health Hospital of Jiaxing were selected as study objects.All of them were singletons.The patients were grouped according to the cause of acute pancreatitis and the severity of the disease.The pregnancy outcomes and neonatal conditions were analyzed.
Results:Of 62 patients with acute pancreatitis, 40 cases (64.52%) had full-term delivery, 20 cases (32.26%) had premature delivery, and 2 cases(3.22%) had intrauterine fetal death.The newborns included in the study were 60 cases.There were no statistically significant differences in the proportion of premature infants between different morbidity factors, neonatal birth weight and neonatal disease composition (the premature infants: F=0.691, P=0.352; birth weight: F=1.042, P=0.382; biliary erythremia: F=1.382, P=0.521; respiratory distress syndrome: F=0.496, P=0.584; hypoglycemia: F=3.102, P=0.165; infectious disease: F=0.895, P=0.124; intracranial hemorrhage: F=0.004, P=0.932). The difference of termination pregnancy rate was statistically significant (biliary 57.69%, hyperlipidemia 82.14%, other 25.00%) (F=12.541, P=0.000), and the rate of the lipemia group was the highest (82.14%). The proportion of premature infants with moderate pregnancy and acute pancreatitis was the highest (75.0%), and the birth weight was the lowest (F=8.142, 4.581, P=0.000, 0.001). The proportion of termination of pregnancy among different degrees of disease had no statistically significant difference (mild 12.19%, moderate 75.0%, and severe 69.23%) (F=1.251, P=0.4125). The intracranial hemorrhage (0.00%), neonatal respiratory distress syndrome (2.44%) and infectious disease rate (4.88%) were the lowest in mild pregnancy with acute pancreatitis (F=8.641, 7.362, 6.982, P=0.000, 0.000, 0.000).
Conclusion:Pregnancy with acute pancreatitis can cause adverse pregnancy outcomes and affect the health of newborns.As the patients' condition worsens, the adverse outcome will be more serious.
