Efficacy of treadmill training on neuropsychiatric symptoms and quality of life among elderly Alzheimer's disease
10.3760/cma.j.issn.1672-7088.2019.23.004
- VernacularTitle: 跑步机训练对老年阿尔茨海默病患者神经精神症状与生命质量的影响
- Author:
Rubing LIANG
1
;
Yiping LIN
2
;
Junhong LUO
1
Author Information
1. Quanzhou Medical College, Quanzhou 362000, China
2. Department of Neurology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China
- Publication Type:Clinical Trail
- Keywords:
Treadmill training;
Neuropsychiatric symptoms;
Quality of life;
Alzheimer′s disease
- From:
Chinese Journal of Practical Nursing
2019;35(23):1779-1784
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze effect of Treadmill Training on neuropsychiatric symptoms and quality of life in elderly patients with Alzheimer′s disease.
Methods:From May 2018 to November 2018, the experimental design was adopted. The patients with 55-75 years old AD, the First Affiliated Hospital of Quanzhou Fujian Medical University were randomly divided into groups. Group (treadmill training, 68 patients), control group (no intervention, 68 patients). The two groups were evaluated before the training and 20 weeks after training, using the Neuropsychology Scale (NPI-Q) and the Alzheimer's disease Quality of Life Questionnaire (QOL-AD), and the t-test, two-factor repeated measures analysis of variance, etc. Statistical methods for data analysis.
Results:There were no significant differences in neuropsychiatric scores and QOL scores between the two groups before training (P>0.05). After training through a 20-week treadmill, the total score of neuropsychiatric symptoms in patients with Alzheimer's disease in the experimental group (t=-1.317, P=0.204 before training; t=-10.01, P=0.046 after 20 weeks of training), affective symptoms (Before training, t=-1.684, P=0.092; t=-11.26, P=0.043 after 20 weeks of training, psychiatric symptoms (t=1.168 before training, P=0.235; t=-9.94 after training for 20 weeks, P=0.034)), behavioral symptoms (t=1.952 before training, P=0.129; t=-3.61, P=0.028 after 20 weeks of training), and QOL total score (t=1.452, P=0.140 before training; t=22.27 after training, P=0.040) were statistically different; and the improvement of neuropsychiatric symptoms in the experimental group was significantly different from that in the control group (F=23.10, P=0.000), while the QOL of the experimental group was also significantly different from the control group (t=- 8.88, P=0.000).
Conclusion:Non-pharmacological treatment with treadmill training can improve neuropsychiatric symptoms and improve quality of life in elderly AD patients.
