Progress on PM2.5 and its adverse impact on lung tissues
10.3760/cma.j.issn.2095-428X.2019.23.018
- VernacularTitle: PM2.5及其对肺组织损伤的研究进展
- Author:
Xiang DENG
1
;
Xingliang ZHANG
1
,
2
;
Lingli ZHANG
3
;
Xiancheng WANG
1
,
4
;
Lawei YANG
1
;
Yuge HUANG
1
;
Jianxin TAN
1
Author Information
1. Department of Pediatrics, the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
2. Institute of Pediatrics, Shenzhen Children′s Hospital, Shenzhen 518038, Guangdong Province, China
3. Department of Gynaecology and Obstetrics, the Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
4. Department of Pediatrics, Shenzhen Hospital of Medical University, Shenzhen 518110, Guangdong Province, China
- Publication Type:Review
- Keywords:
PM2.5;
Pulmonary injury;
Pulmonary surfactant protein
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(23):1828-1830
- CountryChina
- Language:Chinese
-
Abstract:
The atmospheric particulate matter(PM) is widely regarded as one of major environmentally and unfriendly ambient air pollution, and therein PM2.5 (diameter≤2.5 μm) is most closely related to human health.Because of its smaller diameter with longer suspension duration, PM can absorb many pathogenic microorganisms, and easily enter into the deep of airway and then deposit on the bronchus and alveoli, and it brings damage to the lung tissues and the surfactant proteins.PM can give rise to oxidative stress, inflammation response, cells and DNA damage.Now, this review focuses on the characterization and composition of PM, as well as the impact of PM2.5 on the lung, surfactant proteins and human health, which helps to call for more people to pay attention to this environmental issue in order to better mitigate and prevent the damage caused by PM.
