Correlation between cord blood vitamin D level and recurrent respiratory tract infection in infants
10.3760/cma.j.issn.1008-6706.2019.22.012
- VernacularTitle: 脐血维生素D水平与婴儿反复呼吸道感染的相关性分析
- Author:
Hejia GE
1
;
Junguo CHEN
;
Ming WU
;
Yiqun TENG
Author Information
1. Department of Pediatrics, the Second Hospital of Jiaxing, Jiaxing, Zhejiang 314000, China
- Publication Type:Journal Article
- Keywords:
Fetal blood;
Infant;
25-hydroxy vitamin D;
Respiratory tract infections
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(22):2736-2739
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between cord blood vitamin D level and recurrent respiratory tract infection in infants.
Methods:From August 2014 to July 2015, 298 neonates in the Second Hospital of Jiaxing were selected in this study.The serum levels of 25-hydroxyvitamin D[25(OH)D] were measured by enzyme-linked immunosorbent assay(ELISA) in umbilical cord blood of neonates.The incidence of respiratory tract infection in infants was followed up.
Results:There were 53.1%(158/298) newborns with vitamin D deficiency(deficiency group), 24.8%(74/298) neonates with inadequate vitamin D(inadequate group), 22.1%(66/298) infants with adequate vitamin D(adequate group). The incidence rates of recurrent respiratory infections in vitamin D deficiency group, inadequate group and adequate group were 29.7%(47/158), 17.6%(13/74), 10.6%(7/66), respectively.The incidence of recurrent respiratory tract infection among the three groups was statistically significantly different(χ2=11.114, P=0.01).
Conclusion:Vitamin D nutrition level of neonates has a significant correlation with infants with respiratory tract infection, especially lower respiratory tract infection.Therefore, it is necessary to pay attention to the supplement and detection of vitamin D during pregnancy, so as to reduce the incidence of infant respiratory diseases in the region.
