Clinical analysis of 20 cases with Jakohanmer's esophagus
10.3760/cma.j.issn.1008-6706.2019.22.004
- VernacularTitle: 杰克汉默食管20例临床分析
- Author:
Danhong WANG
1
;
Wenguo CHEN
2
Author Information
1. Department of Gastroenterology, the People's Hospital of Yuhuan, Yuhuan, Zhejiang 317600, China
2. Department of Gastroenterology, the First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang 310003, China
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux;
Jackhammer esophagus;
Proton pump inhibitor;
JE-gastroesophageal reflux disease;
Esophagus;
Dynamic pH value;
Acid allergy esophagus;
oesophagitis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(22):2703-2707
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the prevalence and characteristics of Jackhammer esophagus (JE).
Methods:From December 2015 to December 2018, the clinical data of 20 patients with JE in the People's Hospital of Yuhuan were retrospectively analyzed.The clinical data of JE patients with typical symptoms of proton pump inhibitor reactive gastroesophageal reflux disease (GERD) were evaluated.The differences between JE patients with or without GERD or allergic esophagus were analyzed, which including esophagogastroscopy (EGD), dynamic pH impedance monitoring of proton pump inhibitors and proton pump inhibitor tests.
Results:Of 20 patients with JE, the average age was (55.86±3.23) years old, and BMI was (26.10±3.21)kg/m2.Among JE patients, 10 cases (50.0%) were GERD positive, 2 cases (10.0%) were acid sensitive esophagus, and 8 cases (40.0%) were GERD negative.There were no statistically significant differences in heartburn (P=0.167), nausea (P=0.250), dysphagia (P=0.714) or non-cardiac chest pain (P=0.906) and their duration (P=0.319) among the three types of patients.It also affected the intake of proton pump inhibitor (P=0.377) and heartburn (P=0.494). The total number of reflux in patients with positive GERD caused by JE proton pump inhibitor was significantly increased (P=0.027).
Conclusion:JE has a low prevalence rate in patients with typical symptoms of GERD and proton pump inhibitor treatment response.In this study, only nearly half of the people were diagnosed as GERD positive, which indicates that additional objective tests are needed to stratify JE phenotypes.
