Clinical value of non-invasive ventilator in the treatment of bronchial asthma with pneumonia
10.3760/cma.j.issn.1008-6706.2019.21.009
- VernacularTitle: 无创呼吸机在支气管哮喘合并肺炎治疗中的应用价值
- Author:
Xiaoyu CHEN
1
Author Information
1. Department of Respiratory Diseases, the Second People's Hospital of Yiwu, Yiwu, Zhejiang 322000, China
- Publication Type:Journal Article
- Keywords:
Asthma;
Pneumonia;
Ventilators, mechanical;
Blood gas analysis;
Lung function;
Airway function
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(21):2597-2601
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical value of non-invasive ventilator in the treatment of bronchial asthma with pneumonia.
Methods:From June 2016 to June 2018, a total of 90 patients with bronchial asthma complicated with pneumonia admitted to the Second People's Hospital of Yiwu were enrolled in this study.The patients were randomly divided into observation group and control group according to the digital table, with 45 cases in each group.The control group received routine treatment and nursing.The observation group was given non-invasive ventilator-assisted treatment based on the control group, and both two groups were treated for 7 days.Blood gas indicators[pH value, partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), arterial oxygen saturation (SaO2)], pulmonary function indicators[ACT score, FEV1 occupational vital capacity percentage (FEV1/FVC), exhalation peak flow rate (PEF), lung volume (VC)], airway function indicators[peak volume ratio (PFV), expiratory flow rate/tidal expiratory peak flow rate (25/PF) when exhaled 75% tidal volume, tidal volume (VT), tidal exhalation medium flow rate/tidal inhalation medium flow rate (ME/MI)], complications during treatment and length of hospital stay were compared before and after treatment.
Results:After treatment, PaO2 [(9.12±0.76)kPa], SaO2 [(93.72±7.59)%], ACT score [(23.67±2.13)points], FEV1/FVC[(73.47±5.29)%], PEF[(3.68±0.58)L/s], PFV(50.36±5.27)%, 25/PF(81.36±5.34)%, VT(9.31±1.56)mL/mg, ME/MI(89.12±4.63)% in the observation group were higher than those in the control group [PaO2(7.31±0.43)kPa, SaO2 (86.51±5.51)%, ACT score (17.45±1.89)points, FEV1/FVC (65.24±5.62)%, PEF (2.98±0.42)L/s, PFV (41.31±4.52)%, 25/PF (72.39±5.16)%, VT (7.69±1.65)mL/mg, ME/MI (77.96±3.71)%], the differences were statistically significant (t=13.905, 5.157, 14.653, 7.153, 6.557, 8.744, 8.103, 4.786, 10.357, all P<0.05). The incidence of complications (28.89%) and hospitalization time [(11.36±2.31)d] in the observation group were lower than those in the control group [55.56%, (15.46±2.68)d], the differences were statistically significant (t=6.559, 7.773, allP<0.05).
Conclusion:Non-invasive ventilator can effectively improve the blood gas index of patients with bronchial asthma complicated with pneumonia, improve lung function and airway function, reduce the incidence of complications, reduce hospitalization time, and promote the early recovery of patients.It is worthy of promoting.
