The clinical value of oblique lateral interbody fusion in lumbar degenerative diseases: a meta-analysis
10.3760/cma.j.issn.0253-2352.2019.21.004
- VernacularTitle: 斜外侧腰椎椎间融合术治疗腰椎退行性疾病疗效的meta分析
- Author:
Chong TANG
1
;
Zheng LIU
;
Sijun WU
;
Zhenpeng GUAN
;
Zheng PEI
;
Wenlong WANG
;
Shuo ZHANG
Author Information
1. The Department of Orthopaedics, Peking University Shougang Hospital, Beijing 100144, China
- Publication Type:Clinical Trail
- Keywords:
Lumbar vertebrae;
Spinal fusion;
Meta-analysis
- From:
Chinese Journal of Orthopaedics
2019;39(21):1320-1332
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and efficacy of oblique lateral interbody fusion (OLIF) in the surgical treatment of lumbar degenerative diseases.
Methods:All literatures of OLIF performed in lumbar degenerative diseases were searched in recognized databases including Pubmed, OVID, Embase, Cochrane Library, Science Direct, springer, CNKI, Wanfang and VIP databases. Methodological Indexfor Non-randomized Studies (MINORS) was used to evaluate the quality of the literatures. The meta-analysis was performed using Review Manager 5.3 and Stata 15.0 statistical software.
Results:A total of 35 literatures were included, including 22 English literatures and 13 Chinese literatures. There were 3 630 patients with 45.2% of males, aged from 14 to 89 years old (mean, 62.6 years). The average of length of stay (LOS), operation time (OT) and blood loss (BL) of OLIF procedure were 6.7 days, 117 minutes, and 128 ml, respectively. The VAS scores of low back pain of postoperative and final follow-up decreased by 4.33 and 4.70, respectively. The VAS scores of leg pain decreased by 4.57 points and 5.31, respectively. Compared with preoperative, the postoperative JOA score increased by 7.58 and the postoperative ODI were also improved by 33.89%. All the postoperative imaging data were significantly different from those before surgery. The surgical level intervertebral heightincreased 4.14 mm, and the intervertebral foramen height and intervertebral foramen area increased by 3.54 mm, 53.96 mm2, while the dura sac cross-sectional area increased by 36.61 mm2, and the overall lumbar lordosis increased by 13.78° with the local segmental lordosis increased by 4.62°. The overall incidence of complications of OLIF was 32%, with a 95% confidence interval of 25%-38%.
Conclusion:OLIF is a minimally invasive procedure for the treatment of lumbar degenerative diseases. OLIF has a simply procedure and short learning curve, with short LOS and operation time, less blood loss. OLIF can effectively open the narrow intervertebral space and increase the spinal canal and nerve root canal, significantly improve the symptoms, while the complication rate is low, so OLIF is worthy of widespread clinical application.
