Effect of accelerated rehabilitation surgery management combined with thymalfasin on rehabilitation quality of patients undergoing laparoscopic radical nephrectomy
10.3760/cma.j.issn.1008-6706.2019.20.020
- VernacularTitle: 加速康复外科管理联合胸腺法新对腹腔镜肾癌根治术患者康复质量的影响
- Author:
Jialuo DENG
1
Author Information
1. Department of Surgery, the People's Hospital of Renshou County, Sichuan 620500, China
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Radical nephrectomy;
Urologic surgical procedures;
Laparoscopy;
Clinical protocols;
Perioperative care;
Thymalfasin;
Rehabilitation
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(20):2523-2527
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of enhanced recovery after surgery program with thymalfasin in patients undergoing laparoscopic radical nephrectomy in the perioperative period to enhance the quality of rehabilitation and reduce the risk of surgical complications.
Methods:Retrospective analysis of the clinical data of 156 patients undergoing radical laparoscopic radical nephrectomy in the People's Hospital of Renshou County from August 2013 to June 2018 was conducted.According to the perioperative management plan, 74 patients were divided into control group(74cases) and observation group(82cases). Laparoscopic surgery was performed in both two groups.The perioperative period of the observation group was accelerated surgical rehabilitation, and thymalfasin was given before and after surgery.The control group used a traditional perioperative management program.The blood loss, postoperative recovery time and complications were compared between the two groups.
Results:The loss of hemoglobin during operation[(11.90±5.61)g/L]in the accelerated rehabilitation group was slightly lower than that of the control group[(17.47±5.31)g/L], and the indwelling time of plasma drainage tube, anal exhaust time and hospitalization time in the accelerated rehabilitation group were (35.96±4.47)h, (12.61±4.05)h, (121.45±4.30)h, respectively, which were significantly shorter than those in the control group[(46.81±4.55)h, (15.34±4.45)h, (193.69±5.48)h], the differences were statistically significant (t=6.351, 15.011, 4.012, 92.043, all P<0.05).
Conclusion:Enhanced recovery after surgery program with thymalfasin in patients undergoing laparoscopic radical nephrectomy is a safe and effective treatment.The use of thymalfasin method can accelerate the recovery of patients' immune function, and the accelerated rehabilitation program with thymalfasin can effectively reduce the probability of infection during surgery, which can effectively reduce the possibility of infection during operation, accelerate the recovery of physiological function, shorten the hospital stay of patients and improve the quality of rehabilitation of patients.
