Clinical effect of Shiquan Dabu Decoction combined with nitroglycerin on acute heart failure after myocardial infarction
10.3760/cma.j.issn.1008-6706.2019.20.001
- VernacularTitle: 十全大补汤加减联合硝酸甘油治疗急性心肌梗死后心力衰竭的临床效果分析
- Author:
Tianming BAI
1
;
Changlin ZHAI
2
;
Wenyu CHEN
3
Author Information
1. Department of Cardiology, the Traditional Chinese Medicine Hospital of Lishui, Lishui, Zhejiang 323000, China
2. Department of Cardiology, the First Hospital of Jiaxing, Jiaxing, Zhejiang 314001, China
3. Department of Respiration, the First Hospital of Jiaxing, Jiaxing, Zhejiang 314001, China
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Heart failure;
Shiquan Dabu Tang;
Nitroglycerin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(20):2433-2436
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize and discuss the clinical effect of Shiquan Dabu Decoction combined with nitroglycerin in the treatment of heart failure after acute myocardial infarction.
Methods:From January 2016 to June 2017, 110 patients with heart failure after acute myocardial infarction admitted to the Department of Cardiology of Lishui Hospital of Traditional Chinese Medicine were selected as study objects.The patients were randomly divided into observation group and control group according to the digital table, with 55 cases in each group.The control group was treated with routine nitroglycerin therapy, while the observation group was treated with routine nitroglycerin therapy combined with Shiquan Dabu Decoction.The therapeutic effect of the two groups after one week of treatment was observed.
Results:The total effective rate in the observation group was 92.73%, which was significantly higher than that of the control group(78.18%), and the difference between the two groups was statistically significant(χ2=4.681, P<0.05). The HR level of the observation group[(82.5±6.5)times/min] was significantly lower than that of the control group[(102.6±3.9)times/min](t=19.655, P<0.01). The levels of SBP[(116.5±6.4)mmHg]and SpO2[(95.2±1.6)%] in the observation group were significantly higher than those in the control group[(108.8±5.2)mmHg, (92.5±1.2)%], there were statistically significant differences between the two groups(t=6.925, 10.012, all P<0.01). The incidence of adverse reaction in the observation group was 10.91%, which was higher than that in the control group(3.64%), but there was no statistically significant difference (χ2=2.157, P>0.05).
Conclusion:For patients with heart failure after acute myocardial infarction, the combination of traditional Chinese medicine Shiquan Dabu Decoction in clinical routine treatment has better effect and is worthy of popularizing.
