Progresses in pharmaceutical and surgical management of premature ejaculation
10.1097/CM9.0000000000000433
- Author:
Qin-Bo HU
1
;
Dong ZHANG
2
;
Liang MA
3
;
Derry Mingyao NG
2
;
Maria HALEEM
2
;
Qi MA
3
,
4
Author Information
1. Department of Reproductive Medicine, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China
2. School of Medicine, Ningbo University, Ningbo, Zhejiang 315000, China
3. Translational Research Laboratory for Urology, The Key Laboratory of Ningbo City, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China
4. Department of Urology, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China
- Publication Type:Review
- Keywords:
Premature ejaculation;
Selective serotonin reuptake inhibitors;
Penile dorsal nerve neurotomy
- From:
Chinese Medical Journal
2019;132(19):2362-2372
- CountryChina
- Language:English
-
Abstract:
Objective:Premature ejaculation (PE) is regarded as one of the most common male sexual dysfunctions. This review introduced several pharmaceutical and surgical methods for the management of PE. The definition, etiology, behavioral, and psychological therapy of PE were also discussed.
Data sources:"Premature," "ejaculation," or "sexual dysfuction" were used as the medical subject headings (MeSH) to obtain relevant articles before June 2019 on Pubmed, Google Scholar and CNKI. Most articles used were written in English and several Chinese articles were also cited.
Study selection:Full-text articles of retrospective/prospective/randomized controlled trials were analyzed. Animal experiments and letters were excluded.
Results:There are four PE sub-types: lifelong PE, acquired PE, natural variable PE, and subjective PE. Behavioral therapy, psychotherapy, medication, topical anesthetics, and surgery are currently used for the treatment of PE. However, all the above treatments have limitations. Therefore, novel ways should be investigated to more efficiently control PE.
Conclusions:The pharmaceutical therapy that is currently being used in clinical practice for the management of PE is still the main choice globally due to its good efficacy. Surgery may be a choice for patients who are resistant to medication. However, it should be performed cautiously.
